SCHEMBL14389990

SCHEMBL14389990

Nc1ccn([C@H]2C[C@@H](O)[C@@H](COP(=O)(S)O[C@@H]3C[C@H](n4cnc5c(N)ncnc54)O[C@@H]3COP(=O)(S)O[C@@H]3C[C@H](n4cnc5c(=O)[nH]c(N)nc54)O[C@@H]3COP(=O)(S)O[C@@H]3C[C@H](n4cnc5c(N)ncnc54)O[C@@H]3CO)O2)c(=O)n1

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ F2 P00734 1/20 0.54
▸ POLB P06746 3/20 0.54
▸ P2RY2 P41231 3/20 0.52
▸ P2RY4 P51582 3/20 0.52
▸ P2RY6 Q15077 3/20 0.52
▸ ENPP1 P22413 3/20 0.49
▸ P2RY1 P47900 1/20 0.49
▸ TERT O14746 1/20 0.49
▸ DTYMK P23919 2/20 0.45
▸ FPR2 P25090 2/20 0.44
▸ DNMT1 P26358 2/20 0.44
▸ DNMT3B Q9UBC3 2/20 0.44
▸ STING1 Q86WV6 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13326124 1.00 F2 (0.54) F2POLBP2RY2P2RY4P2RY6
SCHEMBL14389999 1.00 F2 (0.54) F2POLBP2RY2P2RY4P2RY6
SCHEMBL13326155 1.00 F2 (0.54) F2POLBP2RY2P2RY4P2RY6
SCHEMBL13326121 1.00 F2 (0.54) F2POLBP2RY2P2RY4P2RY6
SCHEMBL14389939 1.00 F2 (0.54) F2POLBP2RY2P2RY4P2RY6
SCHEMBL14389873 0.94 POLB (0.60) F2POLBP2RY2P2RY4P2RY6
SCHEMBL13359727 0.94 POLB (0.60) F2POLBP2RY2P2RY4P2RY6
SCHEMBL21489387 0.94 F2 (0.64) F2POLBP2RY2P2RY4P2RY6
SCHEMBL21504636 0.94 F2 (0.64) F2POLBP2RY2P2RY4P2RY6
SCHEMBL26189524 0.94 F2 (0.64) F2POLBP2RY2P2RY4P2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070270359-A1 Nucleic Acid-Based Compounds and Methods of Use Thereof IYER RADHAKRISHNAN P 2007-11-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070270359-A1 Nucleic Acid-Based Compounds and Methods of Use Thereof NT5C3B, HAVCR2, NSUN2 F2 4405/4885POLB 8/4885P2RY2 1506/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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