Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | P2RY2 | P41231 | 4/20 | 0.56 |
| ▸ | P2RY4 | P51582 | 4/20 | 0.56 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.56 |
| ▸ | F2 | P00734 | 2/20 | 0.56 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.46 |
| ▸ | NT5E | P21589 | 2/20 | 0.44 |
| ▸ | POLA1 | P09884 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.42 |
| ▸ | TERT | O14746 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | PNP | P00491 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14389873 | 1.00 | POLB (0.60) | POLBP2RY2P2RY4P2RY6F2 | |
| SCHEMBL13326155 | 0.94 | F2 (0.54) | POLBP2RY2P2RY4P2RY6F2 | |
| SCHEMBL14389999 | 0.94 | F2 (0.54) | POLBP2RY2P2RY4P2RY6F2 | |
| SCHEMBL13326124 | 0.94 | F2 (0.54) | POLBP2RY2P2RY4P2RY6F2 | |
| SCHEMBL14389939 | 0.94 | F2 (0.54) | POLBP2RY2P2RY4P2RY6F2 | |
| SCHEMBL13326121 | 0.94 | F2 (0.54) | POLBP2RY2P2RY4P2RY6F2 | |
| SCHEMBL14389990 | 0.94 | F2 (0.54) | POLBP2RY2P2RY4P2RY6F2 | |
| SCHEMBL8614074 | 0.93 | P2RY2 (0.62) | POLBP2RY2P2RY4P2RY6F2 | |
| SCHEMBL8613676 | 0.93 | P2RY2 (0.62) | POLBP2RY2P2RY4P2RY6F2 | |
| SCHEMBL14389949 | 0.93 | F2 (0.67) | POLBP2RY2P2RY4P2RY6F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7709449-B2 | Nucleic acid-based compounds and methods of use thereof | MIGENIX, INC. (CA) | 2010-05-04 | — | — | US | disclosed |