Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TPH1 | P17752 | 2/20 | 0.38 |
| ▸ | TPH2 | Q8IWU9 | 2/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14390891 | 0.90 | PTGS1 (0.44) | PTGS1LIMK1MAPTMEN1GAA | |
| SCHEMBL3585776 | 0.88 | KDM4E (0.52) | MAPTMEN1GAAKMT2APOLB | |
| SCHEMBL14391019 | 0.84 | PTGS1 (0.39) | PTGS1LIMK1MAPTMEN1GAA | |
| SCHEMBL14390893 | 0.84 | CHEK2 (0.41) | CHEK2CSNK2A1HDAC1MAP4K4RXRA | |
| SCHEMBL14390694 | 0.83 | IKBKB (0.39) | PTGS1LIMK1MAPTMEN1GAA | |
| SCHEMBL14391015 | 0.82 | MEN1 (0.38) | PTGS1LIMK1MAPTMEN1GAA | |
| SCHEMBL14391020 | 0.82 | IKBKB (0.45) | PTGS1MAPTMEN1GAAKMT2A | |
| SCHEMBL14390899 | 0.81 | ADORA2A (0.46) | PTGS1MAPTMEN1GAAKMT2A | |
| SCHEMBL3588813 | 0.78 | KDM4E (0.50) | PTGS1MAPTMEN1GAAKMT2A | |
| SCHEMBL14390897 | 0.75 | CYP3A4 (0.40) | MAPTMEN1KMT2AKDM4EHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007124546-A1 | INTEGRASE INHIBITORS 3 | AVEXA LIMITED (AU) | 2007-11-08 | — | — | WO | disclosed |