Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | GAA | P10253 | 6/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | RXRA | P19793 | 2/20 | 0.38 |
| ▸ | RXRB | P28702 | 2/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14390863 | 0.90 | PTGS1 (0.42) | MEN1KMT2AGAAPOLBPTGS1 | |
| SCHEMBL14390694 | 0.90 | IKBKB (0.39) | MEN1KMT2AGAAPOLBPTGS1 | |
| SCHEMBL3590027 | 0.87 | KDM4E (0.49) | MEN1KMT2AGAAPOLBMAPK1 | |
| SCHEMBL14391012 | 0.82 | CHEK2 (0.41) | MEN1KMT2AGAAPOLBPTGS1 | |
| SCHEMBL14391020 | 0.82 | IKBKB (0.45) | MEN1KMT2AGAAPOLBPTGS1 | |
| SCHEMBL14391019 | 0.81 | PTGS1 (0.39) | MEN1KMT2AGAAPOLBPTGS1 | |
| SCHEMBL14390899 | 0.81 | ADORA2A (0.46) | MEN1KMT2AGAAPOLBPTGS1 | |
| SCHEMBL3594349 | 0.78 | KDM4E (0.49) | MEN1KMT2AGAAPOLBPTGS1 | |
| SCHEMBL3582497 | 0.77 | KDM4E (0.54) | MEN1KMT2AGAAPOLBMAPK1 | |
| SCHEMBL3592534 | 0.74 | POLB (0.43) | MEN1KMT2AGAAPOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007124546-A1 | INTEGRASE INHIBITORS 3 | AVEXA LIMITED (AU) | 2007-11-08 | — | — | WO | disclosed |