Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.38 |
| ▸ | MAPT | P10636 | 9/20 | 0.38 |
| ▸ | MEN1 | O00255 | 9/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.38 |
| ▸ | POLB | P06746 | 8/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | GAA | P10253 | 6/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14391015 | 0.90 | MEN1 (0.38) | IKBKBPTGS1KDM4EMAPTMEN1 | |
| SCHEMBL3582497 | 0.86 | KDM4E (0.54) | KDM4EMAPTMEN1KMT2APOLB | |
| SCHEMBL14391020 | 0.86 | IKBKB (0.45) | IKBKBPTGS1KDM4EMAPTMEN1 | |
| SCHEMBL14391012 | 0.83 | CHEK2 (0.41) | PTGS1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL14390863 | 0.82 | PTGS1 (0.42) | PTGS1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL14390899 | 0.81 | ADORA2A (0.46) | PTGS1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL14391019 | 0.81 | PTGS1 (0.39) | PTGS1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL3590027 | 0.77 | KDM4E (0.49) | KDM4EMAPTMEN1KMT2APOLB | |
| SCHEMBL3592534 | 0.76 | POLB (0.43) | KDM4EMAPTMEN1KMT2APOLB | |
| SCHEMBL14385887 | 0.76 | LIMK1 (0.41) | IKBKBKDM4EMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007124546-A1 | INTEGRASE INHIBITORS 3 | AVEXA LIMITED (AU) | 2007-11-08 | — | — | WO | disclosed |