Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.42 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.42 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | PDE1A | P54750 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3590359 | 0.91 | KMT2A (0.44) | ALDH1A1HPGDKDM4ENPSR1TDP1 | |
| SCHEMBL3584550 | 0.91 | KMT2A (0.44) | ALDH1A1HPGDKDM4ENPSR1TDP1 | |
| SCHEMBL3597444 | 0.88 | PTGES (0.45) | ALDH1A1HPGDKDM4ENPSR1TDP1 | |
| SCHEMBL3597438 | 0.88 | PTGES (0.45) | ALDH1A1HPGDKDM4ENPSR1TDP1 | |
| SCHEMBL3580685 | 0.88 | PDE5A (0.48) | ALDH1A1HPGDKDM4ENPSR1TDP1 | |
| Tromethamine SCHEMBL3598984 | 0.87 | KMT2A (0.42) | ALDH1A1HPGDKDM4ENPSR1TDP1 | |
| Tromethamine SCHEMBL3583622 | 0.87 | KMT2A (0.42) | ALDH1A1HPGDKDM4ENPSR1TDP1 | |
| SCHEMBL3587275 | 0.87 | KMT2A (0.46) | ALDH1A1HPGDKDM4ENPSR1TDP1 | |
| SCHEMBL3589044 | 0.84 | ALDH1A1 (0.43) | ALDH1A1HPGDKDM4ENPSR1TDP1 | |
| SCHEMBL3592516 | 0.83 | ALDH1A1 (0.46) | ALDH1A1HPGDKDM4ENPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007124546-A1 | INTEGRASE INHIBITORS 3 | AVEXA LIMITED (AU) | 2007-11-08 | — | — | WO | disclosed |