Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 14/20 | 0.42 |
| ▸ | GSK3B | P49841 | 7/20 | 0.42 |
| ▸ | WNT1 | P04628 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | CLK3 | P49761 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14391201 | 0.93 | HAO1 (0.38) | HAO1DYRK1AGSK3BWNT1MAPT | |
| SCHEMBL1175808 | 0.82 | HAO1 (0.44) | HAO1DYRK1AGSK3BWNT1CLK2 | |
| SCHEMBL5046343 | 0.82 | HAO1 (0.44) | HAO1DYRK1AGSK3BWNT1CLK2 | |
| SCHEMBL1572791 | 0.81 | HAO1 (0.45) | HAO1DYRK1AGSK3BWNT1CLK2 | |
| SCHEMBL13069257 | 0.81 | DYRK1A (0.51) | DYRK1AGSK3BWNT1 | |
| SCHEMBL14391270 | 0.80 | MAPT (0.46) | DYRK1AGSK3BWNT1MAPTMAPK1 | |
| SCHEMBL14391089 | 0.80 | MAPT (0.46) | DYRK1AGSK3BWNT1MAPTMAPK1 | |
| Formic Acid SCHEMBL5561468 | 0.79 | HAO1 (0.42) | HAO1DYRK1AGSK3BWNT1CLK2 | |
| SCHEMBL14391073 | 0.79 | DYRK1A (0.44) | DYRK1AWNT1MAPTMAPK1 | |
| SCHEMBL14391202 | 0.77 | DYRK1A (0.42) | DYRK1AGSK3BWNT1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697378-B1 | INDOLES, 1H-INDAZOLES, 1,2-BENZISOXAZOLES, AND 1,2-BENZISOTHIAZOLES, AND PREPARATION AND USES THEREOF | MEMORY PHARM CORP (US) | 2007-11-21 | — | — | EP | disclosed |