Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PCNA | P12004 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3142103 | 0.86 | THRB (0.44) | HDAC8ALDH1A1MAPTHSD17B10KMT2A | |
| SCHEMBL14553379 | 0.81 | F2RL1 (0.49) | ALDH1A1MAPTHSD17B10KMT2ALMNA | |
| SCHEMBL8579599 | 0.79 | SKP2 (0.50) | ALDH1A1MAPTKMT2AHTTHPGD | |
| SCHEMBL9861891 | 0.79 | TSHR (0.45) | ALDH1A1MAPTKMT2AHPGDEPHX2 | |
| SCHEMBL1351101 | 0.79 | TSHR (0.48) | EPHX2CYP19A1 | |
| SCHEMBL14629174 | 0.79 | THRA (0.36) | HDAC8ALDH1A1MAPTHSD17B10KMT2A | |
| SCHEMBL8578501 | 0.78 | SKP2 (0.45) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL3131477 | 0.78 | THRB (0.48) | ALDH1A1MAPTHSD17B10KMT2ALMNA | |
| SCHEMBL3911709 | 0.78 | THRB (0.48) | ALDH1A1MAPTHSD17B10KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL1789073 | 0.77 | MAOB (0.47) | EPHX2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007128492-A1 | NOVEL PHARMACEUTICAL COMPOSITIONS | KARO BIO AB (SE) | 2007-11-15 | — | — | WO | disclosed |