Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 12/20 | 0.77 |
| ▸ | HDAC3 | O15379 | 9/20 | 0.77 |
| ▸ | HDAC4 | P56524 | 9/20 | 0.77 |
| ▸ | HDAC7 | Q8WUI4 | 9/20 | 0.77 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.77 |
| ▸ | HDAC10 | Q969S8 | 9/20 | 0.77 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.77 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.77 |
| ▸ | HDAC9 | Q9UKV0 | 9/20 | 0.77 |
| ▸ | HDAC5 | Q9UQL6 | 9/20 | 0.77 |
| ▸ | HDAC11 | Q96DB2 | 8/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trichostatin SCHEMBL19886 | 0.87 | HDAC1 (1.00) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL10324242 | 0.87 | HDAC1 (0.81) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| Trichostatin SCHEMBL16380793 | 0.87 | HDAC1 (1.00) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| Trichostatin SCHEMBL446806 | 0.87 | HDAC1 (1.00) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| Trichostatin SCHEMBL446807 | 0.87 | HDAC1 (1.00) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| Trichostatin SCHEMBL675951 | 0.87 | HDAC1 (1.00) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL17119540 | 0.86 | HDAC1 (0.79) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| Trichostatin SCHEMBL29450582 | 0.86 | HDAC1 (0.97) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL12245785 | 0.84 | HDAC1 (0.76) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL10198759 | 0.84 | HDAC1 (0.76) | HDAC1HDAC3HDAC4HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070254835-A1 | COMPOSITION AND METHOD FOR TREATING NEUROLOGICAL DISORDERS | SUPERGEN INC. | 2007-11-01 | — | — | US | disclosed |