Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 5/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL678546 | 0.85 | PLK1 (0.63) | PLK1GAAPOLBALDH1A1LMNA | |
| SCHEMBL23840710 | 0.84 | ESRRG (0.50) | PLK1LMNAHTTNPC1RAB9A | |
| SCHEMBL17865779 | 0.82 | LMNA (0.58) | POLBLMNAHTT | |
| SCHEMBL24534514 | 0.82 | PLK1 (0.57) | PLK1GAAPOLBCTDSP1ALDH1A1 | |
| SCHEMBL20017310 | 0.81 | LMNA (0.55) | POLBLMNAHTTNPC1RAB9A | |
| SCHEMBL28577923 | 0.81 | EPHX2 (0.58) | PLK1POLBLMNAHTT | |
| SCHEMBL507514 | 0.80 | CA1 (0.50) | PLK1POLBLMNAHTTKMT2A | |
| SCHEMBL22328132 | 0.80 | LMNA (0.50) | PLK1POLBLMNAHTT | |
| SCHEMBL506297 | 0.80 | HDAC3 (0.61) | PLK1LMNAHTTKMT2A | |
| SCHEMBL13761402 | 0.80 | LMNA (0.50) | PLK1POLBLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7300936-B2 | α-(N-sulfonamido)acetamide derivatives as β-amyloid inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-11-27 | — | — | US | disclosed |