Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5233570 | 0.71 | KMT2A (0.47) | MAPTMEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL988 | 0.71 | MAPT (0.50) | TERTALDH1A1MAPTMEN1LMNA | |
| SCHEMBL5233620 | 0.71 | KMT2A (0.48) | ALDH1A1MAPTMEN1LMNAKMT2A | |
| SCHEMBL5233613 | 0.71 | KMT2A (0.48) | ALDH1A1MAPTMEN1LMNAKMT2A | |
| SCHEMBL5236948 | 0.71 | KMT2A (0.48) | ALDH1A1MAPTMEN1LMNAKMT2A | |
| SCHEMBL7003270 | 0.67 | TERT (0.48) | TERTALDH1A1MAPTMEN1LMNA | |
| SCHEMBL3670031 | 0.67 | TERT (0.63) | TERTMAPTLMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL742 | 0.66 | TERT (0.51) | TERTALDH1A1MAPTMEN1LMNA | |
| SCHEMBL5233782 | 0.65 | USP2 (0.48) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12462401 | 0.65 | ALDH1A1 (0.46) | TERTALDH1A1MAPTMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1454897-B1 | PYRAZOLOPYRIMIDINONE DERIVATIVES HAVING PDE7-INHIBITORY ACTIVITY | ASUBIO PHARMA CO LTD (JP) | 2007-10-10 | — | — | EP | disclosed |