Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | ATP4A | P20648 | 2/20 | 0.36 |
| ▸ | ATP4B | P51164 | 2/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14395497 | 0.88 | ATP4A (0.39) | BRD4ESR2ABL1ALOX5ATP4A | |
| SCHEMBL276547 | 0.83 | PTPN1 (0.46) | BRD4ESR2ABL1ALOX5NPC1 | |
| SCHEMBL14395501 | 0.83 | BRD4 (0.40) | BRD4ESR2ABL1ALOX5ATP4A | |
| SCHEMBL14395810 | 0.82 | ABL1 (0.36) | ABL1ALOX5NPC1RAB9AKMT2A | |
| SCHEMBL27849101 | 0.77 | CHRNA7 (0.42) | BRD4ESR2ABL1ALOX5NPC1 | |
| SCHEMBL13090192 | 0.73 | NPC1 (0.39) | ABL1NPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL13720657 | 0.71 | HSP90AA1 (0.43) | NPC1POLBSMN1; SMN2KMT2AGAA | |
| SCHEMBL277107 | 0.69 | ABL1 (0.36) | ABL1ALOX5HTR3EHTR3BHTR3A | |
| SCHEMBL277106 | 0.69 | ABL1 (0.36) | ABL1ALOX5HTR3EHTR3BHTR3A | |
| Hydrochloric Acid SCHEMBL2641005 | 0.69 | ABL1 (0.35) | ABL1ALOX5HTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1845090-A1 | AMIDE COMPOUND AND THROMBOPOIETIN RECEPTOR ACTIVATOR | Nissan Chemical Industries, Ltd. (JP) | 2007-10-17 | — | — | EP | disclosed |