SCHEMBL276547

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14395501	0.85	BRD4 (0.40)	PTPN1PTGS2ABL1SMN1; SMN2NPC1
	SCHEMBL27849101	0.85	CHRNA7 (0.42)	PTPN1PTGS2ABL1SMN1; SMN2NPC1
	SCHEMBL16471130	0.84	AKR1C2 (0.43)	SMN1; SMN2NPC1RAB9AMAPTHPGD
	SCHEMBL14396014	0.83	BRD4 (0.38)	PTPN1PTGS2ABL1SMN1; SMN2NPC1
	SCHEMBL1783988	0.82	TRPM8 (0.47)	SMN1; SMN2NPC1RAB9AKMT2AMAOB
	SCHEMBL14395497	0.82	ATP4A (0.39)	PTPN1PTGS2ABL1SMN1; SMN2NPC1
	SCHEMBL277465	0.81	ABL1 (0.40)	ABL1SMN1; SMN2NPC1RAB9APOLB
	SCHEMBL280393	0.81	MAPT (0.53)	PTPN1SMN1; SMN2NPC1RAB9APOLB
	SCHEMBL277337	0.81	ABL1 (0.44)	ABL1NPC1RAB9AKMT2ARORB
	SCHEMBL1484281	0.79	ALDH1A1 (0.43)	SMN1; SMN2KMT2ARORBRORCMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.