Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | GABRP | O00591 | 2/20 | 0.46 |
| ▸ | GABRD | O14764 | 2/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.46 |
| ▸ | GABRE | P78334 | 2/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.46 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.46 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.46 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL7600562 | 0.98 | TSHR (0.56) | TSHRGABRPGABRDGABRA1GABRB1 | |
| Hydrochloric Acid SCHEMBL3958573 | 0.98 | TSHR (0.56) | TSHRGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL3545285 | 0.94 | TSHR (0.56) | TSHRGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL21467667 | 0.92 | TSHR (0.54) | TSHRGABRPGABRDGABRA1GABRB1 | |
| Hydrochloric Acid SCHEMBL1232427 | 0.92 | TSHR (0.54) | TSHRGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL24804137 | 0.86 | — | — | |
| SCHEMBL18116498 | 0.86 | — | — | |
| SCHEMBL205336 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL247260 | 0.84 | GABRP (0.54) | TSHRGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL1354938 | 0.84 | GABRP (0.48) | TSHRGABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116496224-B | 4-Quinazolinone hydroxamic acid derivative, pharmaceutical composition and application thereof | 武汉思瓴生物科技有限公司 | 2024-11-01 | — | — | CN | disclosed |
| CN-116496224-A | 4-quinazolinone hydroxamic acid derivative, pharmaceutical composition and application thereof | 武汉思瓴生物科技有限公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-106349156-A | Pyridine-2-amides capable of being used as CB2 agonist | 霍夫曼-拉罗奇有限公司 | 2017-01-25 | — | — | CN | disclosed |
| CN-103608332-B | Pyridine-2-amides useful as CB2 agonists | 霍夫曼-拉罗奇有限公司 | 2016-09-28 | — | — | CN | disclosed |
| US-8263044-B2 | Stilbene like compounds as novel HDAC inhibitors | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2012-09-11 | — | — | US | disclosed |
| WO-2007054776-A9 | STILBENE LIKE COMPOUNDS AS NOVEL HDAC INHIBITORS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2011-03-03 | — | — | WO | disclosed |
| US-20090136431-A1 | Stilbene Like Compounds as Novel HDAC Inhibitors | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2009-05-28 | — | — | US | disclosed |
| WO-2007054776-A2 | STILBENE LIKE COMPOUNDS AS NOVEL HDAC INHIBITORS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090136431-A1 | Stilbene Like Compounds as Novel HDAC Inhibitors | HDAC1, HDAC5, HDAC11 | TSHR 3925/4885GABRP 4187/4885GABRD 4712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.