⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18116498 | 1.00 | — | — | |
| SCHEMBL24804137 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL30244719 | 0.98 | GABRP (0.54) | — | |
| Hydrochloric Acid SCHEMBL247260 | 0.98 | GABRP (0.54) | — | |
| SCHEMBL1439617 | 0.86 | TSHR (0.58) | — | |
| SCHEMBL3545285 | 0.85 | TSHR (0.56) | — | |
| Hydrochloric Acid SCHEMBL3958573 | 0.85 | TSHR (0.56) | — | |
| Iodide SCHEMBL7600562 | 0.85 | TSHR (0.56) | — | |
| SCHEMBL18116497 | 0.84 | SLC1A1 (0.45) | — | |
| SCHEMBL4957134 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912677-A2 | PSMA ANTIBODY-DRUG CONJUGATES | Psma Development Company, L.L.C. (US) | 2008-04-23 | — | — | EP | claimed |
| WO-2007002222-A2 | PSMA ANTIBODY-DRUG CONJUGATES | PSMA DEVELOPMENT COMPANY, LLC (US) | 2007-01-04 | — | — | WO | claimed |
| CN-116003285-A | Water-soluble prodrug derivatives of phenolic TRPV1 agonists, compositions, preparation methods and uses thereof | 江苏恩华络康药物研发有限公司 | 2023-04-25 | — | — | CN | disclosed |
| EP-4001276-A1 | AURORA KINASE INHIBITOR AND USE THEREOF | Wigen Biomedicine Technology (Shanghai) Co., Ltd. (CN) | 2022-05-25 | — | — | EP | disclosed |
| CN-110845385-B | Synthesis method of (R) -5-methyl pyrrolidone-2-ketone | 苏州永健生物医药有限公司 | 2022-03-04 | — | — | CN | disclosed |
| CN-111793011-B | Styrene sulfone NLRP3 inflammatory corpuscle inhibitor and preparation method and application thereof | 山东大学 | 2021-08-20 | — | — | CN | disclosed |
| US-10941113-B2 | Sulfamoyl-arylamides and the use thereof as medicaments for the treatment of hepatitis B | JANSSEN SCIENCES IRELAND UC (IE) | 2021-03-09 | — | — | US | disclosed |
| WO-2021008338-A1 | AURORA KINASE INHIBITOR AND USE THEREOF | 微境生物医药科技(上海)有限公司 | 2021-01-21 | — | — | WO | disclosed |
| CN-111793011-A | Styrene sulfone NLRP3 inflammatory corpuscle inhibitor and preparation method and application thereof | 山东大学 | 2020-10-20 | — | — | CN | disclosed |
| CN-110845385-A | Synthesis method of (R) -5-methyl pyrrolidone-2-ketone | 苏州永健生物医药有限公司 | 2020-02-28 | — | — | CN | disclosed |
| CN-109943207-A | A kind of modified polyurea coating | 浙江中科应化科技有限公司 | 2019-06-28 | — | — | CN | disclosed |
| US-20080015370-A1 | Process for the conversion of a crude glycerol, crude mixtures of naturally derived multicomponent aliphatic hydrocarbons or esters thereof to a chlorohydrin | BLUE CUBE IP LLC | 2008-01-17 | — | — | US | disclosed |
| CN-1976886-A | Conversion of multihydroxylated-aliphatic hydrocarbon or ester thereof to chlorohydrin | DOW GLOBAL TECHNOLOGIES INC (US) | 2007-06-06 | — | — | CN | disclosed |
| EP-1771403-A1 | CONVERSION OF A MULTIHYDROXYLATED-ALIPHATIC HYDROCARBON OR ESTER THEREOF TO A CHLOROHYDRIN | Dow Gloval Technologies Inc. (US) | 2007-04-11 | — | — | EP | disclosed |
| EP-1740954-A1 | MASS SPECTROMETRY OF ANTIBODY CONJUGATES | Kadkhodayan, Miryam (US) | 2007-01-10 | — | — | EP | disclosed |
| WO-2006020234-A1 | CONVERSION OF A MULTIHYDROXYLATED-ALIPHATIC HYDROCARBON OR ESTER THEREOF TO A CHLOROHYDRIN | DOW GLOBAL TECHNOLOGIES INC. (US) | 2006-02-23 | — | — | WO | disclosed |
| WO-2005101017-A1 | MASS SPECTROMETRY OF ANTIBODY CONJUGATES | GENENTECH, INC. (US) | 2005-10-27 | — | — | WO | disclosed |
| EP-0573498-A1 | ALIPHATIC PROPARGYLAMINES AS SELECTIVE MAO-B INHIBITORS AND AS NEUROPROTECTIVE AGENTS | UNIVERSITY OF SASKATCHEWAN (CA) | 1993-12-15 | — | — | EP | disclosed |
| WO-1992015551-A1 | ALIPHATIC PROPARGYLAMINES AS SELECTIVE MAO-B INHIBITORS AND AS NEUROPROTECTIVE AGENTS | UNIVERSITY OF SASKATCHEWAN (CA) | 1992-09-17 | — | — | WO | disclosed |
| US-4391816-A | ANTIDIABETIC AGENTS | AYERST, MCKENNA & HARRISON INC. (CA) | 1983-07-05 | — | — | US | disclosed |