Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.63 |
| ▸ | KCNQ2 | O43526 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | ATM | Q13315 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | PIM1 | P11309 | 2/20 | 0.59 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4318899 | 0.86 | KCNQ2 (0.68) | GAANPSR1L3MBTL1KCNQ2KMT2A | |
| SCHEMBL1646808 | 0.85 | CHEK1 (0.55) | — | |
| SCHEMBL10144751 | 0.84 | L3MBTL1 (0.66) | GAANPSR1L3MBTL1KCNQ2KMT2A | |
| SCHEMBL9424190 | 0.84 | GAA (0.59) | GAANPSR1L3MBTL1KCNQ2KMT2A | |
| SCHEMBL865190 | 0.83 | ALDH1A1 (0.62) | GAANPSR1L3MBTL1KMT2AMAPT | |
| SCHEMBL1643994 | 0.83 | NPSR1 (0.68) | GAANPSR1L3MBTL1KCNQ2KMT2A | |
| Hydrochloric Acid SCHEMBL2023240 | 0.80 | POLB (0.76) | GAANPSR1KMT2AMAPTPOLB | |
| SCHEMBL20862436 | 0.80 | GAA (0.69) | GAANPSR1L3MBTL1KCNQ2KMT2A | |
| SCHEMBL13763656 | 0.80 | NPSR1 (0.65) | GAANPSR1L3MBTL1KCNQ2KMT2A | |
| SCHEMBL29955086 | 0.80 | KCNQ2 (0.74) | GAANPSR1L3MBTL1KCNQ2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112300172-B | Bruton tyrosine kinase inhibitors | 比奥根MA公司 | 2024-01-16 | — | — | CN | disclosed |
| WO-2011029046-A1 | BRUTON'S TYROSINE KINASE INHIBITORS | BIOGEN IDEC MA INC. (US) | 2011-03-10 | — | — | WO | disclosed |