Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6401258 | 0.94 | LPAR1 (0.37) | CETPLMNAHDAC1HDAC6ACHE | |
| SCHEMBL5275145 | 0.85 | LPAR1 (0.43) | MEP1BS1PR1 | |
| SCHEMBL13009752 | 0.85 | MAPT (0.42) | LMNAACHEMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13009651 | 0.82 | ABCB1 (0.46) | LMNAMEP1BMEN1KMT2AMAPT | |
| SCHEMBL13009864 | 0.82 | BCHE (0.42) | LMNAACHEMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13009801 | 0.81 | CETP (0.44) | CETPLMNATP53LTB4R2ACHE | |
| SCHEMBL13009787 | 0.81 | LMNA (0.38) | CETPLMNATP53ACHEMEN1 | |
| SCHEMBL13009903 | 0.81 | MTNR1B (0.42) | MEP1BMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL13009871 | 0.80 | MAPT (0.39) | CETPLMNATP53ACHEMEN1 | |
| SCHEMBL13009844 | 0.80 | MAPT (0.40) | CETPLMNAACHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1368301-B1 | SIDE-CHAIN HALOGENATED AMINO CARBOXYLIC ACID DERIVATIVES AS MEDICAMENTS FOR TREATING CARDIOVASCULAR DISEASES | BAYER HEALTHCARE AG (DE) | 2007-10-31 | — | — | EP | disclosed |