SCHEMBL143970

SCHEMBL143970

O=C1Cc2ccccc2N1c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 1.00
GAA P10253 7/20 0.62
TLR9 Q9NR96 2/20 0.62
PKM P14618 1/20 0.62
TNKS O95271 1/20 0.53
KMT2A Q03164 5/20 0.49
MEN1 O00255 4/20 0.49
NOTUM Q6P988 1/20 0.49
CASP6 P55212 4/20 0.47
CASP3 P42574 2/20 0.47
SENP8 Q96LD8 2/20 0.47
SENP7 Q9BQF6 2/20 0.47
SENP6 Q9GZR1 2/20 0.47
TDP1 Q9NUW8 1/20 0.47
ADRA2A P08913 1/20 0.47
ADRA2B P18089 1/20 0.47
ADRA2C P18825 1/20 0.47
ALDH1A1 P00352 4/20 0.47
HTR7 P34969 2/20 0.47
HTR1A P08908 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31422646 1.00 HPGD (1.00) HPGDGAATLR9PKMTNKS
SCHEMBL8539515 0.91 HPGD (0.83) HPGDGAATLR9PKMTNKS
SCHEMBL16456324 0.85 HPGD (0.74) HPGDGAATLR9PKMTNKS
SCHEMBL206755 0.85 HPGD (0.74) HPGDGAATLR9PKMTNKS
SCHEMBL6328308 0.85 HPGD (0.74) HPGDGAATLR9PKMTNKS
SCHEMBL6765903 0.85 HPGD (0.74) HPGDGAATLR9PKMTNKS
SCHEMBL6327688 0.85 HPGD (0.74) HPGDGAATLR9PKMTNKS
SCHEMBL4463146 0.85 HPGD (0.74) HPGDGAATLR9PKMTNKS
SCHEMBL4422153 0.85 HPGD (0.74) HPGDGAATLR9PKMKMT2A
SCHEMBL30420919 0.83 HPGD (0.70) HPGDGAATLR9PKMTNKS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122013529-A Water-based thermoplastic sizing agent doped with nano material, and preparation method and application thereof 浙江理工大学 2026-05-12 CN claimed
JP-59184159-A None JP disclosed
JP-59167548-A None JP disclosed
CN-117924298-B Spiro indolone derivative diastereomer and preparation method and application thereof 苏州大学 2026-05-19 CN disclosed
CN-122013529-A Water-based thermoplastic sizing agent doped with nano material, and preparation method and application thereof 浙江理工大学 2026-05-12 CN disclosed
WO-2025039354-A1 INTERMEDIATE COMPOUND OF OXCARBAZEPINE AND PREPARATION METHOD THEREFOR 浙江九洲药业股份有限公司 2025-02-27 WO disclosed
CN-119504480-A Oxcarbazepine intermediate compound and preparation method thereof 浙江九洲药业股份有限公司 2025-02-25 CN disclosed
CN-118184701-A Phosphono-substituted 3-methyleneoxindole compound and preparation and application thereof 浙江工业大学 2024-06-14 CN disclosed
CN-117924298-A Spiro indolone derivative diastereomer and preparation method and application thereof 苏州大学 2024-04-26 CN disclosed
CN-113773243-B Method for preparing isoindigo compounds by organic catalytic oxidation of indole self-condensation 大连理工大学 2023-01-06 CN disclosed
EP-0104860-B1 1-PHENYL-2(1H,3H)-INDOLONE PSYCHO-THERAPEUTIC AGENTS PFIZER INC. (US) 1987-03-18 EP disclosed
EP-0089426-B1 2-AMINO-6-BIPHENYLACETIC ACIDS A.H. ROBINS COMPANY, INCORPORATED (US) 1986-06-11 EP disclosed
JP-S59184159-A 5-ACYL-1-PHENYL-2-INDOLINONE DERIVATIVE HOKURIKU SEIYAKU CO LTD 1984-10-19 JP disclosed
US-4476307-A Heteroylidene indolone compounds PFIZER INC. (US) 1984-10-09 US disclosed
JP-S59167548-A 5-BENZOYL-2-ANILINO SUBSTITUTED-PHENYLACETIC ACID DERIVATIVE HOKURIKU SEIYAKU CO LTD 1984-09-21 JP disclosed
EP-0104860-A1 1-Phenyl-2(1H,3H)-indolone psycho-therapeutic agents PFIZER INC. (US) 1984-04-04 EP disclosed
EP-0104860-A1 1-Phenyl-2(1H,3H)-indolone psycho-therapeutic agents PFIZER INC. (US) 1984-04-04 EP disclosed
US-4440785-A Methods of using 2-aminobiphenylacetic acids, esters, and metal salts thereof to treat inflammation A. H. ROBINS COMPANY, INC. (US) 1984-04-03 US disclosed
EP-0089426-A1 2-Amino-6-biphenylacetic acids A.H. ROBINS COMPANY, INCORPORATED (US) 1983-09-28 EP disclosed
US-4333951-A MUSCLE RELAXANTS, ANTIINFLAMMATORY AGENTS A. H. ROBINS COMPANY, INC. (US) 1982-06-08 US disclosed