Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC2 | Q13490 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.42 |
| ▸ | PLD1 | Q13393 | 3/20 | 0.42 |
| ▸ | PLD2 | O14939 | 2/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 6/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | UGCG | Q16739 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26814687 | 0.82 | CHRNB2 (0.48) | BIRC2PLD1PLD2HRH4DPP4 | |
| SCHEMBL14164982 | 0.82 | CHRNB2 (0.48) | BIRC2PLD1PLD2HRH4DPP4 | |
| SCHEMBL14165240 | 0.82 | CHRNB2 (0.48) | BIRC2PLD1PLD2HRH4DPP4 | |
| SCHEMBL4236961 | 0.80 | EPHX2 (0.47) | EPHX2CYP3A4 | |
| SCHEMBL16435181 | 0.80 | EPHX2 (0.47) | EPHX2CYP3A4 | |
| SCHEMBL14865199 | 0.77 | PLD1 (0.40) | BIRC2PLD1PLD2HRH4CYP3A4 | |
| SCHEMBL16509278 | 0.75 | BIRC2 (0.56) | BIRC2EPHX2HRH4 | |
| SCHEMBL28923130 | 0.75 | BIRC2 (0.56) | BIRC2EPHX2HRH4 | |
| SCHEMBL22828732 | 0.75 | BIRC2 (0.56) | BIRC2EPHX2HRH4 | |
| SCHEMBL19672749 | 0.75 | EPHX2 (0.47) | EPHX2DPP4CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007111921-A1 | 1-PHENYLSULFONYL-DIAZA HETEROCYCLIC AMIDE COMPOUNDS AND THEIR USES AS MODULATORS OF HYDROXSTEROID DEHYDROGENASES | AMGEN INC. (US) | 2007-10-04 | — | — | WO | disclosed |