Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | GRK5 | P34947 | 1/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 2/20 | 0.31 |
| ▸ | CA7 | P43166 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | ALPL | P05186 | 1/20 | 0.30 |
| ▸ | ALPI | P09923 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14397035 | 0.77 | RET (0.36) | RETGRK5TYRO3DYRK1BCA12 | |
| SCHEMBL12292070 | 0.77 | RET (0.37) | RETGRK5TYRO3DYRK1BCA12 | |
| SCHEMBL14397240 | 0.76 | ELANE (0.35) | CA2CA9 | |
| SCHEMBL14397242 | 0.75 | RET (0.37) | RETGRK5TYRO3DYRK1BCA12 | |
| SCHEMBL12292065 | 0.74 | RET (0.39) | RETGRK5TYRO3DYRK1BCA12 | |
| SCHEMBL14397241 | 0.73 | ELANE (0.40) | CA12CA9 | |
| SCHEMBL645346 | 0.72 | RET (0.53) | RETGRK5TYRO3DYRK1BCA12 | |
| SCHEMBL12292104 | 0.68 | RET (0.40) | RETGRK5TYRO3DYRK1BCA12 | |
| SCHEMBL2936736 | 0.68 | KMT2A (0.42) | CA12CA1CA2CA4CA7 | |
| SCHEMBL14397234 | 0.68 | LMNA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007113119-A1 | 3-AMINO-1,2-BENZISOTHIAZOLE COMPOUNDS FOR COMBATING ANIMAL PEST | BASF SE (DE) | 2007-10-11 | — | — | WO | disclosed |