Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17922508 | 0.85 | NISCH (0.45) | KMT2AACHEADRA2BNISCHTP53 | |
| SCHEMBL11951614 | 0.84 | NISCH (0.46) | KMT2ACA1CA2ALDH1A1ALOX12 | |
| SCHEMBL10932877 | 0.84 | CA2 (0.52) | KMT2ACA1CA2CA7CA9 | |
| SCHEMBL11119769 | 0.84 | ALDH1A1 (0.52) | ALDH1A1IRAK4GAAADRA2BTSHR | |
| SCHEMBL22823665 | 0.84 | HTR1A (0.46) | KMT2ACA1CA2CA7CA9 | |
| SCHEMBL10458169 | 0.79 | IRAK4 (0.33) | KMT2ACA1CA2CA7CA9 | |
| SCHEMBL23813151 | 0.77 | ALDH1A1 (0.48) | KMT2AALDH1A1ACHEIRAK4ALOX12 | |
| SCHEMBL4654255 | 0.77 | DRD1 (0.48) | KMT2ACA1CA2CA7CA9 | |
| SCHEMBL2069775 | 0.77 | ALDH1A1 (0.57) | KMT2ACA1CA2CA7CA9 | |
| SCHEMBL29591819 | 0.77 | ALDH1A1 (0.57) | KMT2ACA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999685-B | Liquid crystal compound containing dicyclohexyl, preparation method, composition and element | 西安近代化学研究所 | 2023-05-02 | — | — | CN | disclosed |
| CN-113999685-A | Liquid crystal compound containing bicyclohexene group, preparation method, composition and element | 西安近代化学研究所 | 2022-02-01 | — | — | CN | disclosed |
| CN-112759509-A | Compound, liquid crystal composition and display device | 阜阳欣奕华材料科技有限公司 | 2021-05-07 | — | — | CN | disclosed |
| CN-110903832-B | Negative liquid crystal compound, liquid crystal composition containing negative liquid crystal compound and application of negative liquid crystal compound | 上海瓜呱科技有限公司 | 2021-02-12 | — | — | CN | disclosed |
| CN-110903832-A | Negative liquid crystal compound, liquid crystal composition containing negative liquid crystal compound and application of negative liquid crystal compound | 上海瓜呱科技有限公司 | 2020-03-24 | — | — | CN | disclosed |
| EP-1852429-B1 | Hexahydro dibenzofuran derivatives | MERCK PATENT GMBH (DE) | 2010-09-15 | — | — | EP | disclosed |
| EP-1043299-B1 | Liquid crystalline compound, liquid crystal composition comprising the liquid crystalline compound, and liquid crystal display device using the liquid crystal composition | CHISSO CORP (JP) | 2008-10-15 | — | — | EP | disclosed |
| US-7417157-B2 | Hexahydrodibenzofuran derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2008-08-26 | — | — | US | disclosed |
| EP-1333017-B1 | Process for the production of alkenes | MERCK PATENT GMBH (DE) | 2008-05-21 | — | — | EP | disclosed |
| EP-1852429-A1 | Hexahydro dibenzofuran derivatives | Merck Patent GmbH (DE) | 2007-11-07 | — | — | EP | disclosed |
| EP-0481317-B1 | Method for dechlorination and/or debromination of aromatic compounds containing fluorine with chlorine and/or bromine | BAYER AG (DE) | 1995-08-09 | — | — | EP | disclosed |
| EP-0363458-B1 | 2,3-DIFLUOROBENZENES | MERCK PATENT GMBH (DE) | 1994-08-03 | — | — | EP | disclosed |
| US-5283378-A | Process for the dechlorination and/or debromination of fluorine-and chlorine- and/or bromine-containing aromatic compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1994-02-01 | — | — | US | disclosed |
| EP-0308438-B1 | LIQUID CRYSTAL PHASE CONTAINING TOLANES | MERCK PATENT GmbH (DE) | 1993-09-29 | — | — | EP | disclosed |
| EP-0481317-A2 | Method for dechlorination and/or debromination of aromatic compounds containing fluorine with chlorine and/or bromine | BAYER AG (DE) | 1992-04-22 | — | — | EP | disclosed |
| US-5087764-A | Deprotonation of a 1-substituted-2,3-difluorobenzene using an organometallic compound and reacting the reaction product with an electrophile | Merck Patent Gesellschaft mit beschrankter Hafung (DE) | 1992-02-11 | — | — | US | disclosed |
| EP-0363458-A1 | 2,3-DIFLUOROBENZENES. | MERCK PATENT GMBH (DE) | 1990-04-18 | — | — | EP | disclosed |
| WO-1989008629-A1 | PROCESS FOR PREPARING 2,3-DIFLUOROBENZENES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-09-21 | — | — | WO | disclosed |
| EP-0308438-A1 | Liquid crystal phase containing tolanes. | MERCK PATENT GMBH (DE) | 1989-03-29 | — | — | EP | disclosed |
| WO-1988007514-A1 | TOLANES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1988-10-06 | — | — | WO | disclosed |