Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 7/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2457021 | 0.94 | NOTUM (0.38) | NOTUMPOLBUSP2CA12CA1 | |
| SCHEMBL1440190 | 0.87 | NOTUM (0.37) | NOTUMPOLBUSP2CA12CA1 | |
| SCHEMBL175762 | 0.81 | NOTUM (0.40) | NOTUMPDK2KDM4ELMNAGAA | |
| SCHEMBL1439934 | 0.79 | AURKA (0.34) | MRGPRX4ALDH1A1 | |
| SCHEMBL254711 | 0.79 | NOTUM (0.33) | NOTUMPOLBUSP2CA12CA1 | |
| SCHEMBL6321184 | 0.76 | NOTUM (0.36) | NOTUMPOLBUSP2CA12CA1 | |
| SCHEMBL1439810 | 0.74 | NOTUM (0.43) | NOTUMCA12CA1CA2CA7 | |
| SCHEMBL1440357 | 0.73 | AURKA (0.32) | — | |
| SCHEMBL6854223 | 0.72 | NOTUM (0.49) | NOTUMPOLBUSP2CA12CA1 | |
| SCHEMBL15675596 | 0.71 | MAPT (0.43) | POLBLMNAGAAL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8350099-B2 | Fluorovinyl ether functionalized aromatic diesters, derivatives thereof, and process for the preparation thereof | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-01-08 | — | — | US | disclosed |
| US-8350099-B2 | Fluorovinyl ether functionalized aromatic diesters, derivatives thereof, and process for the preparation thereof | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-01-08 | — | — | US | disclosed |
| US-8350099-B2 | Fluorovinyl ether functionalized aromatic diesters, derivatives thereof, and process for the preparation thereof | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-01-08 | — | — | US | disclosed |
| EP-2473474-A2 | FLUOROETHER FUNCTIONALIZED AROMATIC DIESTERS AND DERIVATIVES THEREOF | E. I. du Pont de Nemours and Company (US) | 2012-07-11 | — | — | EP | disclosed |
| US-20110218353-A1 | FLUOROVINYL ETHER FUNCTIONALIZED AROMATIC DIESTERS, DERIVATIVES THEREOF, AND PROCESS FOR THE PREPARATION THEREOF | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-09-08 | — | — | US | disclosed |
| US-20110218353-A1 | FLUOROVINYL ETHER FUNCTIONALIZED AROMATIC DIESTERS, DERIVATIVES THEREOF, AND PROCESS FOR THE PREPARATION THEREOF | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-09-08 | — | — | US | disclosed |
| US-20110218353-A1 | FLUOROVINYL ETHER FUNCTIONALIZED AROMATIC DIESTERS, DERIVATIVES THEREOF, AND PROCESS FOR THE PREPARATION THEREOF | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-09-08 | — | — | US | disclosed |
| WO-2011028767-A2 | FLUOROETHER FUNCTIONALIZED AROMATIC DIESTERS AND DERIVATIVES THEREOF | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-03-10 | — | — | WO | disclosed |
| WO-2011028767-A2 | FLUOROETHER FUNCTIONALIZED AROMATIC DIESTERS AND DERIVATIVES THEREOF | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-03-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110218353-A1 | FLUOROVINYL ETHER FUNCTIONALIZED AROMATIC DIESTERS, DERIVATIVES THEREOF, AND PROCESS FOR THE PREPARATION THEREOF | PFAS, PAH, AFF4 | NOTUM 315/4885POLB 2374/4885USP2 2083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.