Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | WDR5 | P61964 | 1/20 | 0.31 |
| ▸ | TPMT | P51580 | 1/20 | 0.31 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2457021 | 0.85 | NOTUM (0.38) | ALDH1A1MRGPRX4 | |
| SCHEMBL1439725 | 0.79 | NOTUM (0.34) | ALDH1A1MRGPRX4 | |
| SCHEMBL1440357 | 0.78 | AURKA (0.32) | AURKATPX2WDR5 | |
| SCHEMBL10179271 | 0.78 | LCK (0.33) | ALDH1A1TSHRHSD17B10 | |
| SCHEMBL15675596 | 0.77 | MAPT (0.43) | ALDH1A1TSHRHSD17B10 | |
| SCHEMBL12330843 | 0.76 | KAT6A (0.36) | MRGPRX4 | |
| SCHEMBL15715137 | 0.74 | ALDH1A1 (0.36) | ALDH1A1TSHRHSD17B10 | |
| SCHEMBL6856136 | 0.74 | AURKA (0.41) | AURKATPX2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL1440099 | 0.72 | ALDH1A1 (0.42) | AURKATPX2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL160267 | 0.72 | PYGL (0.35) | ALDH1A1TSHRHSD17B10TPMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8350099-B2 | Fluorovinyl ether functionalized aromatic diesters, derivatives thereof, and process for the preparation thereof | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-01-08 | — | — | US | disclosed |
| EP-2473474-A2 | FLUOROETHER FUNCTIONALIZED AROMATIC DIESTERS AND DERIVATIVES THEREOF | E. I. du Pont de Nemours and Company (US) | 2012-07-11 | — | — | EP | disclosed |
| US-20110218353-A1 | FLUOROVINYL ETHER FUNCTIONALIZED AROMATIC DIESTERS, DERIVATIVES THEREOF, AND PROCESS FOR THE PREPARATION THEREOF | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-09-08 | — | — | US | disclosed |
| WO-2011028767-A2 | FLUOROETHER FUNCTIONALIZED AROMATIC DIESTERS AND DERIVATIVES THEREOF | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-03-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110218353-A1 | FLUOROVINYL ETHER FUNCTIONALIZED AROMATIC DIESTERS, DERIVATIVES THEREOF, AND PROCESS FOR THE PREPARATION THEREOF | PFAS, PAH, AFF4 | AURKA 1545/4885TPX2 4270/4885ALDH1A1 3438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.