Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 4/20 | 0.38 |
| ▸ | BCHE | P06276 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3591244 | 0.89 | TSHR (0.42) | MAPTTP53TSHRHSD17B10ALDH1A1 | |
| SCHEMBL3585618 | 0.88 | MAPT (0.40) | MAPTTP53TSHRHSD17B10ALDH1A1 | |
| SCHEMBL3586421 | 0.88 | TSHR (0.41) | MAPTTP53TSHRHSD17B10ALDH1A1 | |
| SCHEMBL3598033 | 0.86 | HTT (0.44) | MAPTTP53TSHRHSD17B10ALDH1A1 | |
| SCHEMBL3597285 | 0.85 | MAPT (0.46) | MAPTTP53TSHRHSD17B10ALDH1A1 | |
| SCHEMBL3598118 | 0.85 | ALDH1A1 (0.38) | MAPTTP53TSHRHSD17B10ALDH1A1 | |
| SCHEMBL3594706 | 0.84 | GAA (0.42) | MAPTTP53TSHRHSD17B10ALDH1A1 | |
| SCHEMBL3605624 | 0.84 | GAA (0.41) | MAPTTP53TSHRHSD17B10ALDH1A1 | |
| SCHEMBL3595020 | 0.83 | HSD17B10 (0.52) | MAPTTP53TSHRHSD17B10ALDH1A1 | |
| SCHEMBL3589650 | 0.83 | TSHR (0.41) | MAPTTP53TSHRHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007115231-A2 | CXCR4 MODULATORS | CHEMOCENTRYX, INC. (US) | 2007-10-11 | — | — | WO | disclosed |