Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 11/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL13387751 | 0.91 | GAA (0.43) | MAPK1MAPTGAAALPLRAB9A | |
| SCHEMBL286531 | 0.86 | MAPK1 (0.65) | MAPK1MAPTGAAALPLRAB9A | |
| Hydrochloric Acid SCHEMBL286530 | 0.85 | MAPK1 (0.62) | MAPK1MAPTGAAALPLRAB9A | |
| SCHEMBL14397160 | 0.84 | HCAR3 (0.47) | MAPTALPLRAB9ANPC1CCNA2 | |
| SCHEMBL23854654 | 0.79 | MAPK1 (0.59) | MAPK1MAPTGAAALPLRAB9A | |
| SCHEMBL1662796 | 0.73 | CHEK1 (0.56) | MAPK1MAPTGAAALPLLMNA | |
| SCHEMBL16534089 | 0.72 | MAPK1 (0.51) | MAPK1MAPTGAAALPLRAB9A | |
| SCHEMBL25426462 | 0.70 | NPC1 (0.59) | MAPTRAB9APOLBSMN1; SMN2NPC1 | |
| SCHEMBL23513527 | 0.70 | NPC1 (0.55) | RAB9ASMN1; SMN2NPC1LMNACCNA2 | |
| SCHEMBL4311802 | 0.69 | ALPL (0.55) | MAPTGAAALPLRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007112922-A1 | TRIMERIC, WATER-SOLUBLE AMINOPYRAZOLE COMPOUNDS HAVING AN EFFECT AGAINST NEURODEGENERATIVE DISEASES | PHILIPPS-UNIVERSITÄT MARBURG (DE) | 2007-10-11 | — | — | WO | disclosed |