SCHEMBL14397485

SCHEMBL14397485

CC(=O)c1ccccc1-c1sccc1C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRNP P04156 1/20 0.46
PPARG P37231 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
RXFP1 Q9HBX9 1/20 0.46
NCOR2 Q9Y618 1/20 0.46
KDM4C Q9H3R0 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
ALDH1A1 P00352 4/20 0.42
ALOX15 P16050 2/20 0.42
MYC P01106 1/20 0.41
MEN1 O00255 2/20 0.40
MAPT P10636 2/20 0.40
RECQL P46063 2/20 0.40
KMT2A Q03164 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
HPGD P15428 2/20 0.40
POLB P06746 1/20 0.40
NR4A1 P22736 1/20 0.40
ESR2 Q92731 1/20 0.40
CYP3A4 P08684 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27785956 0.81 MYC (0.50) KDM4CL3MBTL1ALDH1A1ALOX15MYC
SCHEMBL7075388 0.79 ALDH1A1 (0.48) L3MBTL1ALDH1A1ALOX15MEN1MAPT
SCHEMBL14398948 0.78 ALDH1A1 (0.45) ALDH1A1MYCMEN1KMT2ANR4A1
SCHEMBL14398980 0.78 PTGS1 (0.43) RXFP1L3MBTL1ALDH1A1MEN1MAPT
SCHEMBL27725578 0.78 ALDH1A1 (0.45) NPSR1L3MBTL1ALDH1A1ALOX15MYC
SCHEMBL12006047 0.78 MYC (0.54) PRNPPPARGNPSR1RXFP1NCOR2
SCHEMBL14398893 0.78 PRNP (0.47) PRNPPPARGNPSR1RXFP1NCOR2
SCHEMBL9223049 0.78 CYP3A4 (0.60) KDM4CL3MBTL1ALDH1A1ALOX15MYC
SCHEMBL7070868 0.78 DHODH (0.51) L3MBTL1ALDH1A1KMT2ATDP1HPGD
SCHEMBL28947795 0.77 PTPRC (0.48) L3MBTL1ALDH1A1ALOX15MYCKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007117180-A1 AZAHETEROCYCLES, COMBINATORY LIBRARY, FOCUSED LIBRARY, PHARMACEUTICAL COMPOSITION AND METHODS FOR THE PRODUCTION THEREOF 'CHEMICAL DIVERSITY RESEARCH INSTITUTE' LTD. (RU) 2007-10-18 WO disclosed