Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.32 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | PTPRG | P23470 | 1/20 | 0.30 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14398123 | 0.77 | GPR35 (0.34) | GPR35BCAT2PTPN2PTPN1AXL | |
| SCHEMBL14397421 | 0.77 | POLB (0.34) | PTPN2LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL14397797 | 0.75 | GPR35 (0.40) | GPR35BCAT2PTPN2PTPN1AXL | |
| SCHEMBL14397487 | 0.75 | KMT2A (0.36) | L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL14397520 | 0.72 | CYP2C9 (0.34) | PTPN1LMNADHODH | |
| SCHEMBL14398057 | 0.71 | POLB (0.50) | LMNAL3MBTL1ALDH1A1TSHRKMT2A | |
| SCHEMBL2562025 | 0.69 | PTGS1 (0.51) | GPR35BCAT2PTPN2PTPN1AXL | |
| SCHEMBL14397443 | 0.69 | POLB (0.34) | PTPN2PTPN1LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL14398148 | 0.69 | GPR35 (0.38) | GPR35BCAT2PTPN2PTPN1AXL | |
| SCHEMBL14398161 | 0.69 | PRKDC (0.33) | L3MBTL1ALDH1A1KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007117180-A1 | AZAHETEROCYCLES, COMBINATORY LIBRARY, FOCUSED LIBRARY, PHARMACEUTICAL COMPOSITION AND METHODS FOR THE PRODUCTION THEREOF | 'CHEMICAL DIVERSITY RESEARCH INSTITUTE' LTD. (RU) | 2007-10-18 | — | — | WO | disclosed |