SCHEMBL14397643

SCHEMBL14397643

Fc1ccc(Cc2cccc(Br)c2)cc1Cl

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.46
SLC6A4 P31645 1/20 0.43
IDO1 P14902 2/20 0.41
AGXT P21549 2/20 0.41
CYP3A4 P08684 1/20 0.40
MAOB P27338 3/20 0.39
PARP1 P09874 1/20 0.39
MEN1 O00255 1/20 0.38
MAPT P10636 1/20 0.38
KMT2A Q03164 1/20 0.38
PIK3CA P42336 1/20 0.37
SOS1 Q07889 1/20 0.37
EGFR P00533 1/20 0.37
ERBB2 P04626 1/20 0.37
CNR1 P21554 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3890987 0.82 TAAR1 (0.47) TAAR1IDO1AGXTMAOBPARP1
SCHEMBL1043112 0.82 CALM1 (0.48) SLC6A4CYP3A4MAOBPARP1MEN1
Hydrochloric Acid SCHEMBL27607326 0.80 CALM1 (0.46) SLC6A4CYP3A4MAOBPARP1MEN1
SCHEMBL9200966 0.79 TAAR1 (0.60) TAAR1IDO1AGXTMAOB
SCHEMBL754462 0.78 MAOB (0.54) TAAR1IDO1AGXTMAOBMAPT
SCHEMBL9351968 0.75 TAAR1 (0.52) TAAR1IDO1AGXTMAOBPARP1
SCHEMBL29442825 0.73 MEN1 (0.47) CYP3A4PARP1MEN1MAPTKMT2A
SCHEMBL28701298 0.73 MEN1 (0.47) CYP3A4PARP1MEN1MAPTKMT2A
SCHEMBL31499406 0.73 CALM1 (0.57) TAAR1IDO1AGXTMAOB
SCHEMBL4717 0.73 CALM1 (0.57) TAAR1IDO1AGXTMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007113327-A2 FUNGICIDE N-CYCLOPROPYL-SULFONYLAMIDE DERIVATIVES BAYER CROPSCIENCE SA (FR) 2007-10-11 WO disclosed