SCHEMBL9351968

SCHEMBL9351968

Brc1ccc(Cc2cccc(Br)c2)cc1

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.52
IDO1 P14902 2/20 0.50
AGXT P21549 2/20 0.50
MAOB P27338 2/20 0.50
HCAR2 Q8TDS4 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
PARP1 P09874 1/20 0.43
EGFR P00533 1/20 0.42
ERBB2 P04626 1/20 0.42
IDH1 O75874 1/20 0.42
CALM1 P0DP23 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9200966 0.91 TAAR1 (0.60) TAAR1IDO1AGXTMAOBHCAR2
SCHEMBL31499406 0.88 CALM1 (0.57) TAAR1IDO1AGXTMAOBHCAR2
SCHEMBL4717 0.88 CALM1 (0.57) TAAR1IDO1AGXTMAOBHCAR2
SCHEMBL754462 0.85 MAOB (0.54) TAAR1IDO1AGXTMAOBSMN1; SMN2
SCHEMBL1631126 0.85 MAOB (0.54) TAAR1IDO1AGXTMAOBSMN1; SMN2
SCHEMBL3890987 0.85 TAAR1 (0.47) TAAR1IDO1AGXTMAOBHCAR2
SCHEMBL1539285 0.85 TAAR1 (0.52) TAAR1IDO1AGXTMAOBSMN1; SMN2
SCHEMBL10877182 0.83 TRPA1 (0.41) TAAR1IDO1MAOBIDH1CALM1
SCHEMBL24622240 0.81 CA1 (0.54) TAAR1MAOBTDP1PARP1IDH1
SCHEMBL1773320 0.81 ALDH1A1 (0.50) TAAR1IDO1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0347878-B1 Method for manufacturing polyamide resin TOSOH CORP (JP) 1994-09-07 EP claimed
US-4948864-A Catalytic method for manufacturing aromatic polyester resin from aromatic diol, aromatic dibromide and carbon monoxide TOSOH CORPORATION (JP) 1990-08-14 US claimed
US-4937313-A Method for manufacturing polyamide resin from unsaturated bis-amide and arylene dihalide TOSOH CORPORATION (JP) 1990-06-26 US claimed
EP-0355840-A2 Method for manufacturing aromatic polyester resin Tosoh Corporation (JP) 1990-02-28 EP claimed
EP-0347878-A2 Method for manufacturing polyamide resin Tosoh Corporation (JP) 1989-12-27 EP claimed
EP-0347878-B1 Method for manufacturing polyamide resin TOSOH CORP (JP) 1994-09-07 EP disclosed
US-4948864-A Catalytic method for manufacturing aromatic polyester resin from aromatic diol, aromatic dibromide and carbon monoxide TOSOH CORPORATION (JP) 1990-08-14 US disclosed
US-4937313-A Method for manufacturing polyamide resin from unsaturated bis-amide and arylene dihalide TOSOH CORPORATION (JP) 1990-06-26 US disclosed
EP-0355840-A2 Method for manufacturing aromatic polyester resin Tosoh Corporation (JP) 1990-02-28 EP disclosed
EP-0347878-A2 Method for manufacturing polyamide resin Tosoh Corporation (JP) 1989-12-27 EP disclosed