Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | GHSR | Q92847 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13245955 | 0.92 | KMT2A (0.46) | KMT2AALDH1A1KDM4EGHSRLMNA | |
| SCHEMBL13245954 | 0.92 | KMT2A (0.46) | KMT2AALDH1A1KDM4EGHSRLMNA | |
| SCHEMBL13245965 | 0.90 | AAK1 (0.47) | KMT2AALDH1A1KDM4EGHSRLMNA | |
| SCHEMBL13245969 | 0.90 | AAK1 (0.47) | KMT2AALDH1A1KDM4EGHSRLMNA | |
| Hydrochloric Acid SCHEMBL2987425 | 0.90 | AAK1 (0.47) | KMT2AALDH1A1KDM4EGHSRLMNA | |
| SCHEMBL13245971 | 0.88 | ALDH1A1 (0.45) | KMT2AALDH1A1KDM4EGHSRLMNA | |
| SCHEMBL13245956 | 0.86 | ALDH1A1 (0.50) | KMT2AALDH1A1KDM4EGHSRLMNA | |
| SCHEMBL13245951 | 0.86 | ALDH1A1 (0.46) | KMT2AALDH1A1KDM4EGHSRLMNA | |
| SCHEMBL2994634 | 0.85 | ALDH1A1 (0.45) | KMT2AALDH1A1KDM4EGHSRLMNA | |
| SCHEMBL2994636 | 0.85 | ALDH1A1 (0.45) | KMT2AALDH1A1KDM4EGHSRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007118852-A1 | ARYL AND HETEROARYL SULPHONAMIDES AS GROWTH HORMONE SECRETAGOGUE RECEPTOR AGONISTS | GLAXO GROUP LIMITED (GB) | 2007-10-25 | — | — | WO | disclosed |