Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | GHSR | Q92847 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | CASR | P41180 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13245955 | 0.88 | KMT2A (0.46) | ALDH1A1KDM4EPOLBMAPK1SMN1; SMN2 | |
| SCHEMBL13245954 | 0.88 | KMT2A (0.46) | ALDH1A1KDM4EPOLBMAPK1SMN1; SMN2 | |
| SCHEMBL13245971 | 0.87 | ALDH1A1 (0.45) | ALDH1A1KDM4EPOLBMAPK1SMN1; SMN2 | |
| SCHEMBL2994636 | 0.86 | ALDH1A1 (0.45) | ALDH1A1KDM4EPOLBMAPK1SMN1; SMN2 | |
| SCHEMBL13245965 | 0.86 | AAK1 (0.47) | ALDH1A1KDM4EPOLBMAPK1SMN1; SMN2 | |
| SCHEMBL13245969 | 0.86 | AAK1 (0.47) | ALDH1A1KDM4EPOLBMAPK1SMN1; SMN2 | |
| SCHEMBL14397652 | 0.85 | KMT2A (0.46) | ALDH1A1KDM4EPOLBMAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2987425 | 0.85 | AAK1 (0.47) | ALDH1A1KDM4EPOLBMAPK1SMN1; SMN2 | |
| SCHEMBL13245956 | 0.84 | ALDH1A1 (0.50) | ALDH1A1KDM4EPOLBMAPK1SMN1; SMN2 | |
| SCHEMBL2993989 | 0.82 | ALDH1A1 (0.41) | ALDH1A1KDM4EPOLBMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100179168-A1 | ARYL AND HETEROARYL SULPHONAMIDES AS GROWTH HORMONE SECRETAGOGUE RECEPTOR AGONISTS | BLANEY EMMA LOUISE | 2010-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100179168-A1 | ARYL AND HETEROARYL SULPHONAMIDES AS GROWTH HORMONE SECRETAGOGUE RECEPTOR AGONISTS | GHSR, GHRHR, GIPR | ALDH1A1 2521/4885KDM4E 3009/4885POLB 4727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.