Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7652591 | 0.90 | MAPK1 (0.56) | CYP2C19SMN1; SMN2KDM4EMAPK1KMT2A | |
| SCHEMBL7824993 | 0.86 | KMT2A (0.63) | CYP2C19L3MBTL1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL14397898 | 0.86 | KMT2A (0.58) | CYP2C19L3MBTL1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL29902911 | 0.85 | L3MBTL1 (0.57) | CYP2C19L3MBTL1SMN1; SMN2KDM4EMAPK1 | |
| SCHEMBL15575684 | 0.85 | L3MBTL1 (0.57) | CYP2C19L3MBTL1SMN1; SMN2KDM4EMAPK1 | |
| SCHEMBL14426829 | 0.84 | KDM4E (0.74) | CYP2C19L3MBTL1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL2560604 | 0.84 | CA1 (0.57) | CYP2C19L3MBTL1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL14292038 | 0.83 | L3MBTL1 (0.56) | CYP2C19L3MBTL1SMN1; SMN2KDM4EMAPK1 | |
| SCHEMBL15330325 | 0.83 | CA1 (0.51) | L3MBTL1KDM4EKMT2A | |
| SCHEMBL24420606 | 0.82 | CETP (0.63) | L3MBTL1SMN1; SMN2KDM4EMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |
| WO-2007117180-A1 | AZAHETEROCYCLES, COMBINATORY LIBRARY, FOCUSED LIBRARY, PHARMACEUTICAL COMPOSITION AND METHODS FOR THE PRODUCTION THEREOF | 'CHEMICAL DIVERSITY RESEARCH INSTITUTE' LTD. (RU) | 2007-10-18 | — | — | WO | disclosed |