Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14397889 | 0.90 | CYP2C19 (0.57) | MAPK1CYP2C19KDM4ENPC1RAB9A | |
| SCHEMBL6800486 | 0.86 | ALDH1A1 (0.57) | KDM4ENPC1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL24420606 | 0.86 | CETP (0.63) | MAPK1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21665202 | 0.85 | HTT (0.60) | KDM4ETDP1KMT2AGAAMEN1 | |
| SCHEMBL14397898 | 0.83 | KMT2A (0.58) | CYP2C19KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27548637 | 0.83 | CETP (0.65) | MAPK1KMT2AHDAC3HDAC1HDAC4 | |
| SCHEMBL24074514 | 0.83 | CETP (0.65) | MAPK1KMT2AHDAC3HDAC1HDAC4 | |
| SCHEMBL14857060 | 0.82 | KDM4E (0.59) | KDM4ENPC1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL13033135 | 0.81 | TSHR (0.51) | KDM4ENPC1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL2560604 | 0.81 | CA1 (0.57) | CYP2C19KDM4ENPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492364-B1 | Triazolo and derivatives as chemokine inhibitors | TORAY INDUSTRIES, INC. (JP) | 2002-12-10 | — | — | US | disclosed |
| EP-1067130-A1 | TRIAZOLO DERIVATIVES AND CHEMOKINE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2001-01-10 | — | — | EP | disclosed |