Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.37 |
| ▸ | NPC1 | O15118 | 8/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19067622 | 0.84 | ALDH1A1 (0.40) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL13514067 | 0.83 | RET (0.39) | RAB9ANPC1SMN1; SMN2NOTUMLMNA | |
| SCHEMBL17229342 | 0.82 | SMN1; SMN2 (0.40) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL10130863 | 0.82 | RAB9A (0.42) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL10130868 | 0.78 | ALDH1A1 (0.40) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL13513990 | 0.75 | IDH1 (0.46) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL2791170 | 0.75 | ALDH1A1 (0.43) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL10130675 | 0.71 | NOTUM (0.62) | RAB9ANPC1SMN1; SMN2MAPTNOTUM | |
| SCHEMBL28877063 | 0.70 | ALDH1A1 (0.42) | MAPTALDH1A1HPGDMAPK1KDM4E | |
| SCHEMBL12545820 | 0.68 | ALDH1A1 (0.57) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007115278-A2 | 3,6,11-TRICYCLOLIDE | ENANTA PHARMACEUTICALS, INC. (US) | 2007-10-11 | — | — | WO | disclosed |