Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.48 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | UBE2N | P61088 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10175968 | 0.71 | RECQL (0.75) | RECQLL3MBTL1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL11046960 | 0.67 | ALDH1A1 (0.54) | RECQLL3MBTL1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL5121151 | 0.67 | PTGDR2 (0.64) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL10973486 | 0.67 | SMN1; SMN2 (0.67) | L3MBTL1LMNAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL13024525 | 0.65 | POLB (1.00) | RECQLL3MBTL1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL14398660 | 0.64 | ALDH1A1 (0.44) | RECQLL3MBTL1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL13467800 | 0.64 | L3MBTL1 (0.80) | L3MBTL1LMNAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL99448 | 0.64 | PDE4B (1.00) | L3MBTL1ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL2413943 | 0.64 | PDE4B (0.93) | LMNAALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL5119950 | 0.64 | PTGDR2 (0.85) | POLBMEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007117180-A1 | AZAHETEROCYCLES, COMBINATORY LIBRARY, FOCUSED LIBRARY, PHARMACEUTICAL COMPOSITION AND METHODS FOR THE PRODUCTION THEREOF | 'CHEMICAL DIVERSITY RESEARCH INSTITUTE' LTD. (RU) | 2007-10-18 | — | — | WO | disclosed |