Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | NT5E | P21589 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | TOP2A | P11388 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | PTGES | O14684 | 1/20 | 0.51 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.47 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | F3 | P13726 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | GLI1 | P08151 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14400884 | 1.00 | LMNA (0.54) | LMNANT5EUSP2HIF1ATOP2A | |
| SCHEMBL14400890 | 0.88 | NOS2 (0.42) | LMNANT5EUSP2HIF1ATOP2A | |
| SCHEMBL7747717 | 0.87 | LMNA (0.58) | LMNANT5EUSP2HIF1ATOP2A | |
| SCHEMBL10081999 | 0.87 | PTPN1 (0.52) | LMNANT5EUSP2HIF1ATOP2A | |
| SCHEMBL6715660 | 0.87 | LMNA (0.58) | LMNANT5EUSP2HIF1ATOP2A | |
| SCHEMBL14374330 | 0.86 | LMNA (0.57) | LMNANT5EUSP2HIF1ATOP2A | |
| SCHEMBL5447022 | 0.86 | LMNA (0.57) | LMNANT5EUSP2HIF1ATOP2A | |
| SCHEMBL5448684 | 0.86 | CA9 (0.44) | LMNANT5EPTGESSLC10A1GPBAR1 | |
| SCHEMBL14398790 | 0.86 | GPBAR1 (0.64) | LMNANT5EUSP2HIF1APTPN1 | |
| SCHEMBL5442215 | 0.86 | GPBAR1 (0.64) | LMNANT5EUSP2HIF1APTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007112043-A2 | SYNTHETIC PENTACYCLIC TRITERPENOIDS AND DERIVATIVES OF BETULINIC ACID AND BETULIN | ADVANCED LIFE SCIENCES INC. (US) | 2007-10-04 | — | — | WO | disclosed |