SCHEMBL14399863

SCHEMBL14399863

CNc1ccc(NCCCCCNc2cccc3c2C(=O)c2ccccc2C3=O)c2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.69
SMN1; SMN2 Q16637 4/20 0.69
L3MBTL1 Q9Y468 3/20 0.69
EGFR P00533 2/20 0.69
MAPK1 P28482 2/20 0.69
RAB9A P51151 2/20 0.69
PABPC1 P11940 1/20 0.69
TDP1 Q9NUW8 1/20 0.69
MEN1 O00255 6/20 0.59
KMT2A Q03164 6/20 0.59
POLB P06746 4/20 0.59
ALDH1A1 P00352 4/20 0.59
BLM P54132 2/20 0.59
HTT P42858 2/20 0.59
LMNA P02545 2/20 0.59
RAD52 P43351 2/20 0.59
RECQL P46063 1/20 0.59
NPSR1 Q6W5P4 1/20 0.59
NSD2 O96028 2/20 0.53
FGB P02675 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14371474 0.86 MAPT (0.58) MAPTSMN1; SMN2L3MBTL1EGFRMAPK1
SCHEMBL12658889 0.86 TOP2B (0.59) MAPTSMN1; SMN2L3MBTL1EGFRMAPK1
SCHEMBL12658893 0.86 TOP2B (0.52) MAPTSMN1; SMN2L3MBTL1EGFRMAPK1
SCHEMBL13587207 0.86 MEN1 (0.61) MAPTSMN1; SMN2L3MBTL1EGFRMAPK1
SCHEMBL7853370 0.86 MEN1 (0.61) MAPTSMN1; SMN2L3MBTL1EGFRMAPK1
SCHEMBL7854850 0.86 MEN1 (0.61) MAPTSMN1; SMN2L3MBTL1EGFRMAPK1
SCHEMBL1898424 0.86 MEN1 (0.61) MAPTSMN1; SMN2L3MBTL1EGFRMAPK1
SCHEMBL23787768 0.84 MEN1 (0.54) MAPTSMN1; SMN2L3MBTL1EGFRMAPK1
SCHEMBL11310247 0.84 MEN1 (0.54) MAPTSMN1; SMN2L3MBTL1EGFRMAPK1
SCHEMBL45259 0.84 MEN1 (0.63) MAPTSMN1; SMN2L3MBTL1EGFRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7288121-B2 Composition comprising at least one mixed dye comprising at least one chromophore chosen from compounds of the methine family and/or the carbonyl family, dyeing process and kit, and mixed dyes L'OREAL S.A. (FR) 2007-10-30 US disclosed