Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 9/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14399854 | 0.90 | SERPINE1 (0.47) | SERPINE1HRH3MAPT | |
| SCHEMBL13979781 | 0.90 | SERPINE1 (0.49) | SERPINE1HRH3ALOX5MAPT | |
| SCHEMBL13979780 | 0.90 | SERPINE1 (0.49) | SERPINE1HRH3MAPT | |
| SCHEMBL13979764 | 0.90 | SERPINE1 (0.49) | SERPINE1HRH3MAPT | |
| SCHEMBL14399873 | 0.89 | SERPINE1 (0.57) | SERPINE1HRH3MAPT | |
| SCHEMBL13979779 | 0.89 | SERPINE1 (0.57) | SERPINE1HRH3MAPT | |
| SCHEMBL6380223 | 0.88 | SERPINE1 (0.67) | SERPINE1HRH3ALOX5AHRMAPT | |
| SCHEMBL6380230 | 0.88 | SERPINE1 (0.67) | SERPINE1HRH3ALOX5AHRMAPT | |
| SCHEMBL14400074 | 0.85 | SERPINE1 (0.45) | SERPINE1HRH3MAPT | |
| SCHEMBL14400068 | 0.84 | SERPINE1 (0.45) | SERPINE1HRH3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7288545-B2 | Piperazinedione compounds | ANGIORX CORPORATION (TW) | 2007-10-30 | — | — | US | disclosed |