Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 6/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12465587 | 0.82 | SMN1; SMN2 (0.39) | SMN1; SMN2S1PR5S1PR4S1PR1S1PR3 | |
| SCHEMBL3396679 | 0.81 | SMN1; SMN2 (0.46) | SMN1; SMN2S1PR5ALDH1A1 | |
| SCHEMBL6975583 | 0.81 | SMN1; SMN2 (0.42) | SMN1; SMN2S1PR5S1PR4S1PR1S1PR3 | |
| SCHEMBL1048787 | 0.79 | SMN1; SMN2 (0.44) | SMN1; SMN2S1PR5S1PR4S1PR1S1PR3 | |
| SCHEMBL321619 | 0.78 | PIK3CD (0.50) | SMN1; SMN2S1PR5LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL28098432 | 0.77 | L3MBTL1 (0.40) | SMN1; SMN2S1PR5LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL855052 | 0.75 | SMN1; SMN2 (0.67) | SMN1; SMN2S1PR5S1PR4S1PR1S1PR3 | |
| SCHEMBL11308867 | 0.75 | SMN1; SMN2 (0.39) | SMN1; SMN2S1PR5LMNAL3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6997154 | 0.74 | SMN1; SMN2 (0.64) | SMN1; SMN2S1PR5S1PR4S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL27035457 | 0.73 | L3MBTL1 (0.42) | SMN1; SMN2LMNAL3MBTL1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2885298-A1 | CHEMICAL PROCESS | Glaxo Group Limited (GB) | 2015-06-24 | — | — | EP | disclosed |
| WO-2014027045-A1 | CHEMICAL PROCESS | GLAXO GROUP LIMITED (GB) | 2014-02-20 | — | — | WO | disclosed |
| WO-2011029896-A1 | METHODS OF PREPARATION OF MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2011-03-17 | — | — | WO | disclosed |
| EP-1747219-A2 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS FIELD OF THE INVENTION | GLAXO GROUP LIMITED (GB) | 2007-01-31 | — | — | EP | disclosed |
| EP-1740177-A2 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005112644-A2 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2005-12-01 | — | — | WO | disclosed |
| WO-2005104745-A2 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2005-11-10 | — | — | WO | disclosed |