SCHEMBL144002

SCHEMBL144002

Fc1c(Cl)c[c]cc1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27833422 0.89
SCHEMBL148680 0.85
SCHEMBL10809899 0.81
SCHEMBL2291930 0.81
SCHEMBL2290046 0.77
SCHEMBL27714209 0.77 PNMT (0.38)
SCHEMBL2288168 0.75 GAA (0.33)
SCHEMBL27669977 0.74
SCHEMBL443318 0.73
SCHEMBL444678 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 443 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3615527-B1 NEW AZAQUINOLINE DERIVATIVES ELANCO ANIMAL HEALTH GMBH (DE) 2024-03-06 EP claimed
CN-110770227-B Novel azaquinoline derivatives 拜耳动物保健有限责任公司 2024-03-01 CN claimed
US-20230320357-A1 METHODS OF PEST CONTROL IN SOYBEAN SYNGENTA PARTICIPATIONS AG (CH) 2023-10-12 US claimed
CN-116283920-A 2, 4-disubstituted pyridine compound and application thereof 贵州医科大学 2023-06-23 CN claimed
CN-110536892-B Novel bicyclic pyrazole derivatives 拜耳动物保健有限责任公司 2023-05-12 CN claimed
CN-108026089-B Isoxazoline substituted benzamides and analogs as pesticides 先正达参股股份有限公司 2021-10-22 CN claimed
US-11130768-B2 Bicyclic pyrazole derivatives BAYER ANIMAL HEALTH GMBH (DE) 2021-09-28 US claimed
EP-3353171-B1 ISOXAZOLINE-SUBSTITUTED BENZAMIDES AND ANALOGUES AS INSECTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2021-09-15 EP claimed
US-20210163459-A1 PESTICIDALLY ACTIVE AZETIDINE SULFONES AMIDE ISOXAZOLINE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2021-06-03 US claimed
EP-3810605-A1 PESTICIDALLY ACTIVE AZETIDINE SULFONES AMIDE ISOXAZOLINE DERIVATIVES Syngenta Crop Protection AG (CH) 2021-04-28 EP claimed
EP-2579724-A2 PESTICIDAL MIXTURES INCLUDING ISOXAZOLINE DERIVATIVES Syngenta Participations AG (CH) 2013-04-17 EP claimed
WO-2012080415-A1 PESTICIDAL MIXTURES SYNGENTA PARTICIPATIONS AG (CH) 2012-06-21 WO claimed
WO-2012080419-A1 PESTICIDAL MIXTURES SYNGENTA PARTICIPATIONS AG (CH) 2012-06-21 WO claimed
WO-2012045700-A1 INSECTICIDAL PYRROLIDIN-YL-ARYL-CARBOXAMIDES SYNGENTA PARTICIPATIONS AG (CH) 2012-04-12 WO claimed
US-20120059016-A1 PIPERIDINE AND PIPERAZINE DERIVATIVES AS AUTOTAXIN INHIBITORS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2012-03-08 US claimed
EP-2414330-A2 PIPERIDINE AND PIPERAZINE DERIVATIVES AS AUTOTAXIN INHIBITORS Merck Patent GmbH (DE) 2012-02-08 EP claimed
WO-2010115491-A2 PIPERIDINE AND PIPERAZINE DERIVATIVES AS AUTOTAXIN INHIBITORS MERCK PATENT GMBH (DE) 2010-10-14 WO claimed
US-20040152903-A1 6-chloro-3-pyridylmethylpropylamine derivatives, preparation process thereof and bactericides KUREHA CORPORATION (JP) 2004-08-05 US claimed
EP-1375483-A1 6-CHLORO-3-PYRIDYLMETHYLPROPYLAMINE DERIVATIVES, PREPARATION PROCESS THEREOF AND BACTERICIDES KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2004-01-02 EP claimed
EP-0017976-A2 Process for preparing imidazole derivatives F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1980-10-29 EP claimed