Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 7/20 | 0.54 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13354771 | 1.00 | TACR1 (0.54) | TACR1SLC1A1TSHRCA1CA2 | |
| Hydrochloric Acid SCHEMBL16993593 | 0.98 | TACR1 (0.53) | TACR1SLC1A1TSHRCA1CA2 | |
| SCHEMBL9569155 | 0.81 | TACR1 (0.54) | TACR1SLC1A1TSHRCA1CA2 | |
| SCHEMBL17786755 | 0.81 | ALDH1A1 (0.44) | TACR1SLC1A1CA1CA2CA7 | |
| SCHEMBL13418948 | 0.81 | TSHR (0.54) | TACR1SLC1A1TSHRCA1CA2 | |
| Hydrochloric Acid SCHEMBL18954360 | 0.81 | CA1 (0.42) | TSHRCA1CA2CA7CA9 | |
| Hydrochloric Acid SCHEMBL4410718 | 0.80 | TACR1 (0.53) | TACR1SLC1A1TSHRCA1CA2 | |
| SCHEMBL17688799 | 0.79 | TACR1 (0.51) | TACR1SLC1A1TSHRCA1CA2 | |
| SCHEMBL13438937 | 0.78 | TSHR (0.42) | TACR1SLC1A1TSHRSLC1A3SLC1A2 | |
| SCHEMBL7095981 | 0.78 | TACR1 (0.75) | TACR1SLC1A1TSHRCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1153034-B1 | GROWTH HORMONE SECRETAGOGUES | LILLY CO ELI (US) | 2007-10-17 | — | — | EP | disclosed |