Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | STS | P08842 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12713212 | 0.89 | TP53 (0.47) | SMN1; SMN2STSTP53POLBMAPT | |
| SCHEMBL12713201 | 0.87 | SMN1; SMN2 (0.46) | SMN1; SMN2STSTP53POLBCNR1 | |
| SCHEMBL14436423 | 0.85 | SMN1; SMN2 (0.47) | SMN1; SMN2STSTP53POLBMAPT | |
| SCHEMBL12713199 | 0.83 | SMN1; SMN2 (0.45) | SMN1; SMN2STSTP53POLBMAPT | |
| SCHEMBL12713213 | 0.82 | SMN1; SMN2 (0.47) | SMN1; SMN2STSTP53POLBMAPT | |
| SCHEMBL12713214 | 0.82 | SMN1; SMN2 (0.46) | SMN1; SMN2STSTP53POLBMAPT | |
| SCHEMBL4553585 | 0.80 | STS (0.52) | SMN1; SMN2STSTP53POLBMAPT | |
| SCHEMBL13948350 | 0.80 | SMN1; SMN2 (0.45) | SMN1; SMN2STSTP53POLBMAPT | |
| SCHEMBL13002965 | 0.79 | SMN1; SMN2 (0.44) | SMN1; SMN2STSTP53POLBMAPT | |
| SCHEMBL4786221 | 0.79 | CNR1 (0.56) | SMN1; SMN2STSTP53POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007115798-A1 | SUBSTITUTED PHENYLPIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS | SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) | 2007-10-18 | — | — | WO | disclosed |