⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11149825 | 0.83 | ALDH1A1 (0.47) | — | |
| SCHEMBL1101930 | 0.80 | — | — | |
| SCHEMBL14003722 | 0.73 | CYP1A2 (0.31) | — | |
| SCHEMBL1996650 | 0.70 | — | — | |
| SCHEMBL17085866 | 0.65 | — | — | |
| SCHEMBL1271486 | 0.62 | CA1 (0.37) | — | |
| SCHEMBL257550 | 0.62 | — | — | |
| SCHEMBL7009281 | 0.61 | SLC6A3 (0.47) | — | |
| SCHEMBL129530 | 0.60 | — | — | |
| SCHEMBL11926805 | 0.59 | SLC6A3 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3352570-B1 | HETEROCYCLIC TRIFLUOROALKENYL COMPOUNDS HAVING A NEMATOCIDAL ACTIVITY, THEIR AGRONOMIC COMPOSITIONS AND USE THEREOF | ISAGRO SPA (IT) | 2020-04-08 | — | — | EP | claimed |
| US-20180271097-A1 | HETEROCYCLIC TRIFLUOROALKENYL COMPOUNDS HAVING A NEMATOCIDAL ACTIVITY, THEIR AGRONOMIC COMPOSITIONS AND USE THEREOF | ISAGRO S.P.A. (IT) | 2018-09-27 | — | — | US | claimed |
| US-20250002487-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | VENTUS THERAPEUTICS U.S., INC. (US) | 2025-01-02 | — | — | US | disclosed |
| US-11839679-B2 | Gamma-diketones for treatment and prevention of aging skin and wrinkles | BIOSPLICE THERAPEUTICS, INC. (US) | 2023-12-12 | — | — | US | disclosed |
| US-20220087917-A1 | GAMMA-DIKETONES FOR TREATMENT AND PREVENTION OF AGING SKIN AND WRINKLES | VICKERS VENTURE FUND VI PTE. LTD. (SG) | 2022-03-24 | — | — | US | disclosed |
| EP-3352570-B1 | HETEROCYCLIC TRIFLUOROALKENYL COMPOUNDS HAVING A NEMATOCIDAL ACTIVITY, THEIR AGRONOMIC COMPOSITIONS AND USE THEREOF | ISAGRO SPA (IT) | 2020-04-08 | — | — | EP | disclosed |
| CN-110294781-A | One kind Schiff of thiadiazolyl group containing ferrocenyl and preparation method thereof | 陕西科技大学 | 2019-10-01 | — | — | CN | disclosed |
| WO-2019051197-A1 | TRPC5 INHIBITORS AND METHODS OF USING SAME | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2019-03-14 | — | — | WO | disclosed |
| CN-104903320-B | Nitrogen-containing heterocycle compound or its salt | 富士胶片株式会社 | 2018-11-13 | — | — | CN | disclosed |
| US-20180271097-A1 | HETEROCYCLIC TRIFLUOROALKENYL COMPOUNDS HAVING A NEMATOCIDAL ACTIVITY, THEIR AGRONOMIC COMPOSITIONS AND USE THEREOF | ISAGRO S.P.A. (IT) | 2018-09-27 | — | — | US | disclosed |
| WO-2018129287-A1 | HETEROARYLDIAZEPINE DERIVATIVES AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2018-07-12 | — | — | WO | disclosed |
| EP-3038622-B1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | MEDIVATION TECH LLC (US) | 2018-05-30 | — | — | EP | disclosed |
| EP-3212640-A1 | COMPOUND HAVING GPR119 AGONISTIC ACTIVITY, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION INCLUDING THE SAME AS EFFECTIVE COMPONENT | Dong-A ST Co., Ltd. (KR) | 2017-09-06 | — | — | EP | disclosed |
| WO-2016068453-A1 | COMPOUND HAVING GPR119 AGONISTIC ACTIVITY, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION INCLUDING THE SAME AS EFFECTIVE COMPONENT | DONG-A ST CO., LTD. (KR) | 2016-05-06 | — | — | WO | disclosed |
| CN-103467462-B | 3-(1,3,4- thiadiazole)-1,3-benzooxazine-2-acetone compounds and application thereof | UNIV HUNAN SCI & TECHNOLOGY | 2015-07-08 | — | — | CN | disclosed |
| CN-103467462-A | 3-(1,3,4- thiadiazole)-1,3-benzooxazine-2-acetone compounds and application thereof | UNIV HUNAN SCI & TECHNOLOGY | 2013-12-25 | — | — | CN | disclosed |
| US-7276520-B2 | Bicyclic piperidine derivatives as melanocortin-4 receptor agonists | MERCK & CO., INC. (US) | 2007-10-02 | — | — | US | disclosed |