SCHEMBL144016

SCHEMBL144016

C[CH]C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
MMP1 P03956 1/20 0.32
MMP2 P08253 1/20 0.32
MMP9 P14780 1/20 0.32
MMP8 P22894 1/20 0.32
MMP13 P45452 1/20 0.32
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1825765 1.00 LMNA (0.38) LMNACA1CA2MMP1MMP2
SCHEMBL415947 1.00 LMNA (0.38) LMNACA1CA2MMP1MMP2
SCHEMBL9718538 1.00 LMNA (0.38) LMNACA1CA2MMP1MMP2
SCHEMBL10345029 1.00 LMNA (0.38) LMNACA1CA2MMP1MMP2
SCHEMBL9718585 1.00 LMNA (0.38) LMNACA1CA2MMP1MMP2
SCHEMBL9718574 1.00 LMNA (0.38) LMNACA1CA2MMP1MMP2
SCHEMBL9718539 1.00 LMNA (0.38) LMNACA1CA2MMP1MMP2
SCHEMBL2252731 1.00 LMNA (0.38) LMNACA1CA2MMP1MMP2
SCHEMBL9718547 1.00 LMNA (0.38) LMNACA1CA2MMP1MMP2
SCHEMBL9718588 1.00 LMNA (0.38) LMNACA1CA2MMP1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2789 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115650990-B Fluorine-containing near infrared absorption cationic phthalocyanine and preparation method thereof 常州大学 2024-03-19 CN claimed
CN-117188039-A Fluorine modified starch glass fiber cotton and preparation method and application thereof 重庆理工大学 2023-12-08 CN claimed
CN-114921158-B Novel polyfluoroether derivative composition 浙江巨化技术中心有限公司 2023-09-15 CN claimed
CN-114276732-B Antibacterial and anticorrosive paint and coating based on silver-doped quaternary ammonium-based nano silica sol and epoxy fluorine-containing acrylate resin 陕西科技大学 2023-03-31 CN claimed
CN-115650990-A Fluorine-containing near-infrared absorption cationic phthalocyanine and preparation method thereof 常州大学 2023-01-31 CN claimed
CN-114921158-A Novel polyfluoroether derivative composition 浙江巨化技术中心有限公司 2022-08-19 CN claimed
CN-114276732-A Antibacterial and anticorrosive paint and coating based on silver-doped quaternary ammonium-based nano silica sol and epoxy fluorine-containing acrylate resin 陕西科技大学 2022-04-05 CN claimed
CN-107778509-B Environment-friendly fluorine coating for solar cell back panel 乐凯胶片股份有限公司 2021-04-09 CN claimed
CN-107266360-B Sulfur-containing unipolar head group double-hydrophobic chain pyridine quaternary ammonium compound and application thereof 华东理工大学 2020-04-03 CN claimed
CN-110511324-A A kind of Concentrated Emulsion Polymerization object preparation method containing sulfonic group alkyl UNIV HUBEI TECHNOLOGY 2019-11-29 CN claimed
EP-1197511-A1 Antireflective composition Shipley Company LLC (US) 2002-04-17 EP claimed
US-20020042020-A1 Antireflective composition SHIPLEY COMPANY L.L.C. (US) 2002-04-11 US claimed
EP-0759457-B1 Weather and soiling-resistant silicone-containing coating composition SHINETSU CHEMICAL CO (JP) 2001-06-13 EP claimed
US-6114440-A EMULSION POLYMERIZING AN AQUEOUS SOLUTION OF A WATER-INSOLUBLE GROUP-BEARING SILICONE RESIN AND A VINYL SILANETRIOL MONOMER; COATED AND CURED INTO A FILM HAVING WEAR AND CHEMICAL RESISTANCE AND WATERPROOFING PROPERTIES SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-09-05 US claimed
US-5973068-A BLEND OF WATER INSOLUBLE SILICONE RESIN AND VINYL MONOMER SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-10-26 US claimed
US-5814703-A ORGANIC RESIN AND SILICONE COMPOUND; PROTECTIVE COATINGS SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-09-29 US claimed
EP-0497369-B1 Contact lens material and contact lens HOYA CORP (JP) 1997-04-02 EP claimed
EP-0759457-A2 Weather and soiling-resistant silicone-containing coating composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 1997-02-26 EP claimed
US-5264465-A Perfluoroalkylalkoxyalkyl (meth)acrylate copolymers with amide monomers HOYA CORPORATION (JP) 1993-11-23 US claimed
EP-0497369-A2 Contact lens material and contact lens HOYA CORPORATION (JP) 1992-08-05 EP claimed