SCHEMBL9718547

SCHEMBL9718547

C[CH]C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
MMP1 P03956 1/20 0.32
MMP2 P08253 1/20 0.32
MMP9 P14780 1/20 0.32
MMP8 P22894 1/20 0.32
MMP13 P45452 1/20 0.32
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL144016 1.00 LMNA (0.38) LMNACA1CA2MMP1MMP2
SCHEMBL1825765 1.00 LMNA (0.38) LMNACA1CA2MMP1MMP2
SCHEMBL415947 1.00 LMNA (0.38) LMNACA1CA2MMP1MMP2
SCHEMBL9718538 1.00 LMNA (0.38) LMNACA1CA2MMP1MMP2
SCHEMBL10345029 1.00 LMNA (0.38) LMNACA1CA2MMP1MMP2
SCHEMBL9718585 1.00 LMNA (0.38) LMNACA1CA2MMP1MMP2
SCHEMBL9718574 1.00 LMNA (0.38) LMNACA1CA2MMP1MMP2
SCHEMBL9718539 1.00 LMNA (0.38) LMNACA1CA2MMP1MMP2
SCHEMBL2252731 1.00 LMNA (0.38) LMNACA1CA2MMP1MMP2
SCHEMBL9718588 1.00 LMNA (0.38) LMNACA1CA2MMP1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5115059-A Terpolymers of alkyl acrylates or methacrylates, an olefinically unsaturated homo or heterocyclic-nitrogen compound and an allyl acrylate or methacrylate CONOCO INC. (US) 1992-05-19 US disclosed
US-5015406-A Pour points, viscosity and viscosity index improving polymers CONOCO (US) 1991-05-14 US disclosed
US-4980435-A POUR POINT DEPRESSANT CONOCO INC. (US) 1990-12-25 US disclosed
US-4954135-A Oil compositions containing terpolymers of alkyl acrylates or methacrylates, an olefinically unsaturated homo or heterocyclic-nitrogen compound and allyl acrylates or methacrylates CONCO INC. (US) 1990-09-04 US disclosed
US-4900569-A POUR POINT DEPRESSANT CONOCO INC. (US) 1990-02-13 US disclosed
US-4886520-A POUR POINT DEPRESSANTS CONOCO, INC. (US) 1989-12-12 US disclosed