SCHEMBL14401657

SCHEMBL14401657

O=Nc1ccc(C2OCCn3cncc32)cc1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP17A1 P05093 1/20 0.33
RIPK1 Q13546 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27759827 0.77 RIPK1 (0.47) CYP17A1RIPK1
SCHEMBL1768946 0.74
SCHEMBL2915311 0.70 SLC6A4 (0.40)
SCHEMBL6117683 0.67 CYP1A2 (0.33) RIPK1
SCHEMBL25951392 0.64 CYP17A1 (0.32) CYP17A1
SCHEMBL2915143 0.63 RIPK1 (0.32) RIPK1
SCHEMBL25632995 0.61 CYP11B1 (0.32)
SCHEMBL15801055 0.60 ALDH1A1 (0.33)
SCHEMBL5572854 0.58 CYP19A1 (0.43) CYP17A1
SCHEMBL27285101 0.58 CYP17A1 (0.42) CYP17A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007116100-A1 CONDENSED IMIDAZOLE DERIVATIVES AS AROMATASE INHIBITORS SPEEDEL EXPERIMENTA AG (CH) 2007-10-18 WO disclosed