Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.30 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1735757 | 0.90 | AR (0.36) | ARGSK3BKMT2AMEN1PDE2A | |
| SCHEMBL12066676 | 0.90 | AR (0.36) | ARGSK3BKMT2AMEN1PDE2A | |
| SCHEMBL1735760 | 0.90 | AR (0.36) | ARGSK3BKMT2AMEN1PDE2A | |
| SCHEMBL1735758 | 0.90 | AR (0.36) | ARGSK3BKMT2AMEN1PDE2A | |
| SCHEMBL13478819 | 0.78 | AR (0.37) | ARKMT2A | |
| SCHEMBL1735451 | 0.75 | AR (0.35) | ARKMT2A | |
| SCHEMBL1735448 | 0.75 | AR (0.35) | ARKMT2A | |
| SCHEMBL1735695 | 0.75 | AR (0.35) | ARKMT2A | |
| SCHEMBL1735462 | 0.70 | AR (0.32) | ARKMT2A | |
| SCHEMBL12156896 | 0.69 | AR (0.38) | ARKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007116922-A1 | A PROCESS FOR PREPARING TETRAHYDROQUINOLINE DERIVATIVES | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2007-10-18 | — | — | WO | disclosed |