SCHEMBL14401868

SCHEMBL14401868

COc1cc(N=Nc2cc(S(=O)(=O)O)c3cccc(S(=O)(=O)O)c3c2)c(C)cc1Nc1nc(S)nc(S)n1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SENP2 Q9HC62 5/20 0.52
▸ SUMO2 P61956 4/20 0.52
▸ SUMO1 P63165 4/20 0.52
▸ SENP7 Q9BQF6 4/20 0.52
▸ ATIC P31939 2/20 0.52
▸ ENPP2 Q13822 4/20 0.38
▸ SENP1 Q9P0U3 4/20 0.36
▸ SENP3 Q9H4L4 2/20 0.35
▸ MPL P40238 1/20 0.35
▸ BRD4 O60885 1/20 0.34
▸ ALK Q9UM73 1/20 0.34
▸ APP P05067 2/20 0.33
▸ MAPT P10636 2/20 0.33
▸ SNCA P37840 2/20 0.33
▸ MEN1 O00255 2/20 0.33
▸ THRB P10828 2/20 0.33
▸ KMT2A Q03164 2/20 0.33
▸ SLC7A11 Q9UPY5 1/20 0.33
▸ LRRK2 Q5S007 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13388978 0.84 SENP2 (0.51) SENP2SUMO2SUMO1SENP7ATIC
SCHEMBL12559144 0.84 SENP2 (0.51) SENP2SUMO2SUMO1SENP7ATIC
SCHEMBL12189776 0.83 ATIC (0.45) SENP2SUMO2SUMO1SENP7ATIC
SCHEMBL12559107 0.83 SUMO2 (0.47) SENP2SUMO2SUMO1SENP7ATIC
SCHEMBL31497272 0.83 SENP2 (0.50) SENP2SUMO2SUMO1SENP7ATIC
SCHEMBL13388669 0.83 SENP2 (0.48) SENP2SUMO2SUMO1SENP7ATIC
SCHEMBL14408044 0.83 SENP2 (0.45) SENP2SUMO2SUMO1SENP7ATIC
SCHEMBL3656757 0.83 SENP2 (0.45) SENP2SUMO2SUMO1SENP7ATIC
SCHEMBL12975964 0.83 SENP2 (0.58) SENP2SUMO2SUMO1SENP7ATIC
SCHEMBL25530018 0.83 SENP2 (0.58) SENP2SUMO2SUMO1SENP7ATIC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7278726-B2 Ink jet recording ink set RICOH COMPANY, LTD. (JP) 2007-10-09 — — US disclosed
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