Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.31 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14402422 | 0.83 | NR3C1 (0.35) | NR3C1PGRNR3C2IDO1TSHR | |
| SCHEMBL13849946 | 0.83 | NR3C1 (0.35) | NR3C1PGRNR3C2IDO1TSHR | |
| SCHEMBL10585919 | 0.80 | PNMT (0.59) | IDO1TSHRPNMTTP53RECQL | |
| SCHEMBL17061809 | 0.80 | IDO1 (0.37) | NR3C1PGRNR3C2IDO1TSHR | |
| SCHEMBL18323882 | 0.80 | CYP3A4 (0.42) | NR3C1PGRNR3C2IDO1TSHR | |
| SCHEMBL16759685 | 0.80 | IDO1 (0.37) | NR3C1PGRNR3C2IDO1TSHR | |
| SCHEMBL15178160 | 0.78 | SLC6A2 (0.52) | HPGDHTT | |
| SCHEMBL17062163 | 0.78 | CYP2D6 (0.42) | IDO1TSHRMDM2PNMTTP53 | |
| SCHEMBL16759370 | 0.78 | CYP2D6 (0.42) | IDO1TSHRMDM2PNMTTP53 | |
| SCHEMBL10585879 | 0.78 | SLC6A2 (0.52) | HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847533-A1 | SIX-MEMBERED HETEROCYCLIC COMPOUND AND THE USE THEREOF | Asahi Kasei Pharma Corporation (JP) | 2007-10-24 | — | — | EP | disclosed |