Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 5/20 | 0.78 |
| ▸ | ABCG2 | Q9UNQ0 | 13/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | GBA1 | P04062 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15658387 | 0.88 | PDE4B (1.00) | PDE4B | |
| SCHEMBL392277 | 0.85 | ABCG2 (0.70) | PDE4BABCG2ABCB1MEN1NPC1 | |
| SCHEMBL14403225 | 0.77 | ABCG2 (0.54) | PDE4BABCG2ABCB1MEN1NPC1 | |
| SCHEMBL15658115 | 0.75 | PDE4B (0.54) | PDE4B | |
| SCHEMBL15948018 | 0.74 | PDE4B (0.77) | PDE4BABCG2ABCB1ABCC1 | |
| Hydrochloric Acid SCHEMBL16669462 | 0.74 | PDE4B (0.76) | PDE4BABCG2ABCB1ABCC1 | |
| SCHEMBL18325185 | 0.72 | L3MBTL1 (0.50) | PDE4BMEN1KMT2A | |
| SCHEMBL15660397 | 0.71 | PDE4B (1.00) | PDE4B | |
| SCHEMBL23586241 | 0.71 | PDE4B (0.56) | PDE4BABCG2ABCB1MEN1NPC1 | |
| SCHEMBL1063729 | 0.71 | PDE4B (0.71) | PDE4BABCG2MEN1KMT2AABCC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007120702-A2 | USE OF GPR119 RECEPTOR AGONISTS FOR INCREASING BONE MASS AND FOR TREATING OSTEOPOROSIS, AND COMBINATION THERAPY RELATING THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2007-10-25 | — | — | WO | disclosed |